Chronic obstructive pulmonary disease (COPD) is a heterogeneous group of lung diseases
limiting the airflow due to narrowing of airways, chronic bronchitis and emphysema that …

Diabetic cardiomyopathy describes decreased myocardial function in diabetic patients in the
absence of other heart diseases such as myocardial ischemia and hypertension. Recent …

Myocardial infarction is the leading cause of morbidity and mortality worldwide. Although
myocardial reperfusion after ischemia (I/R) is an effective method to save ischemic …

O-linked β-N-acetylglucosamine (O-GlcNAcylation) is a dynamic post-translational
modification that regulates thousands of proteins and almost all cellular processes. Aberrant …

The genomic activity of vitamin D is associated with metabolic effects, and the hormone has
a strong impact on several physiological functions and, therefore, on health. Among its …

Data on the effect of vitamin d-calcium co-supplementation on inflammatory biomarkers,
compared to placebo or intake of calcium and vitamin D supplements alone, are conflicting …

The heart is a highly metabolic organ with extensive energy demands and hence relies on
numerous fuel substrates including fatty acids and glucose. However, oxidative stress is a …

Chronic pancreatitis (CP) is a chronic inflammatory and fibrotic disease of the pancreas. The
incidence of CP is increasing worldwide but the effective therapies are lacking. Hence, it is …

Vitamin D (25OHD) pleiotropic effects are widely recognized and studied. Recently, vitamin
D cardiovascular effects are gaining interest, especially in children, although the studies …

Advanced glycation end products (AGEs) are destructive molecules in the body that, at high
levels, contribute to the progression of various chronic diseases. Numerous studies have …