Simple Summary Drug resistance is prevalent in many types of cancer and decreases
patient survival. The taxanes are anti-mitotic chemotherapeutic agents, widely used since …

Prostate cancer (PCa) is heterogeneous, harboring phenotypically diverse cancer cell types.
PCa cell heterogeneity is caused by genomic instability that leads to the clonal competition …

African American men in the United States have higher mortality due to prostate cancer
(PCa) compared to other races. One reason for this disparity is the lack of in-depth …

Abstract Background Prostate cancer (PCa) is one of the leading causes of cancer-related
mortality and morbidity in the aging male population and represents the most frequently …

Prostate cancer (PCa) is the most diagnosed malignancy in the men worldwide. Cancer
stem cells (CSCs) are the sub-population of cells present in the tumor which possess unique …

During the evolution into castration or therapy resistance, prostate cancer cells reprogram
the androgen responses to cope with the diminishing level of androgens, and undergo …

Prostate cancer (PCA) is the leading malignancy in men and the second leading cause of
cancer-related deaths. Hypoxia (low O 2 condition) is considered an early event in prostate …

Approximately, 30 000 men die from prostate cancer (PCa) every year in the United States,
mainly due to the metastasis. Thus, the key events associated with PCa metastasis are …

Prostate cancer (PCa) is the leading malignancy among men in United States. Recent
studies have focused on the identification of novel metabolic characteristics of PCa, aimed at …

Hypoxia is an independent prognostic indicator of poor outcome in several malignancies.
However, precise mechanism through which hypoxia promotes disease aggressiveness is …