Secondary hyperparathyroidism (SHPT) is a challenge frequently encountered in the
management of patients with chronic kidney disease (CKD). Downregulation of the …

The extracellular calcium-sensing receptor (CaSR) plays a major role in the maintenance of
a physiological serum ionized calcium (Ca2+) concentration by regulating the circulating …

Calcium balance is essential for a multitude of physiological processes, ranging from cell
signaling to maintenance of bone health. Adequate intestinal absorption of calcium is a …

Abstract Fibroblast growth factor 23 (FGF23) modulates mineral metabolism by promoting
phosphaturia and decreasing the production of 1, 25-dihydroxyvitamin D 3. FGF23 …

Serum calcium levels are regulated by the action of parathyroid hormone (PTH). Major
drivers of PTH hypersecretion and parathyroid cell proliferation are the hypocalcemia and …

Background The interest on magnesium (Mg) has grown since clinical studies have shown
the efficacy of Mg-containing phosphate binders. However, some concern has arisen for the …

Background Transient postthyroidectomy hypocalcemia occurs in up to 30% of patients. We
evaluated the effect of vitamin D deficiency on postthyroidectomy hypocalcemia. Methods …

Uremic secondary hyperparathyroidism is a multifactorial and complex disease often
present in advanced stages of chronic kidney disease. The accumulation of phosphate, the …

Athletic performance is a heritable trait influenced by both environmental and genetic
factors. Sports genomics is a relatively new scientific discipline focusing on the organization …

A constant extracellular Ca2+ concentration is required for numerous physiological functions
at tissue and cellular levels. This suggests that minor changes in Ca2+ will be corrected by …