Staphylococcus epidermidis is a usually harmless commensal bacterium highly abundant
on the human skin. Under defined predisposing conditions, most importantly implantation of …

The clinical impact of bacterial infections on bone regeneration has been incompletely
quantified and documented. As a result, controversy exists about the optimal treatment …

Osteogenicity (ie, properties that promote new bone formation on and around the implant)
has long been a clinical requirement for most orthopedic implants. Recently, anti-infection or …

Infection of bone tissue, or osteomyelitis, has become a growing concern in modern
healthcare due in no small part to a rise in antibiotic resistance among bacteria, notably …

Elimination of infection and enhancement of osteogenesis by orthopaedic implants are two
critical factors in the treatment of complex bone infections. A prolonged and expensive …

Additively manufactured (AM) porous titanium implants may have an increased risk of
implant-associated infection (IAI) due to their huge internal surfaces. However, the same …

Osteomyelitis is an inflammatory bone disease typically caused by infectious
microorganisms, often bacteria, which causes progressive bone destruction and loss. The …

The development of infections is one of the main complications in orthopaedics, especially
in the presence of implants for the osteosynthesis of compound fractures and joint …

Background To reduce the incidence of osteomyelitis infection, local antibiotic impregnated
delivery systems are commonly used as a promising and effective approach to deliver high …

Aims: the focus of this study is to evaluate if the combination of an antibiotic with a ceramic
biomaterial is effective in treating osteomyelitis in an infected animal model and to define …