Cryo-electron microscopy (CryoEM) has become a vital technique in structural biology. It is
an interdisciplinary field that takes advantage of advances in biochemistry, physics, and …

Single-particle analysis by electron microscopy is a well established technique for analyzing
the three-dimensional structures of biological macromolecules. Besides its ability to produce …

Using a new consensus-based image-processing approach together with principal
component analysis, the flexibility and conformational dynamics of the SARS-CoV-2 spike in …

Structural biology has evolved greatly due to the advances introduced in fields like electron
microscopy. This image-capturing technique, combined with improved algorithms and …

Xmipp is an open-source software package consisting of multiple programs for processing
data originating from electron microscopy and electron tomography, designed and managed …

Abstract The XRCC1–DNA ligase IIIα complex (XL) is critical for DNA single-strand break
repair, a key target for PARP inhibitors in cancer cells deficient in homologous …

Macromolecular assemblies, such as protein complexes, undergo continuous structural
dynamics, including global reconfigurations critical for their function. Two fast analytical …

Understanding how structure and function meet to drive biological processes is
progressively shifting the cryoEM field towards a more advanced analysis of …

Single-particle analysis by electron microscopy is a well established technique for analyzing
the three-dimensional structures of biological macromolecules. Besides its ability to produce …