This review discusses opportunities and bottlenecks for cell factory development of Lactic
Acid Bacteria (LAB), with an emphasis on lactobacilli and pediococci, their metabolism and …

CRISPR-Cas9-based genome engineering tools have revolutionized fundamental research
and biotechnological exploitation of both eukaryotes and prokaryotes. However, the …

Lactic acid bacteria represent a worthwhile organism within the microbial consortium for the
food sector, health, and biotechnological applications. They tend to offer high stability to …

Background Sugars derived from lignocellulose-rich sugarcane bagasse can be used as
feedstock for production of l (+)-lactic acid, a precursor for renewable bioplastics. In our …

Well-developed genetic tools for thermophilic microorganisms are scarce, despite their
industrial and scientific relevance. Whereas highly efficient CRISPR/Cas9-based genome …

Thermophilic bacteria are regarded as attractive production organisms for cost-efficient
conversion of renewable resources to green chemicals, but their genetic accessibility is a …

Synthetic biology can play a major role in the development of sustainable industrial
biotechnology processes. However, the development of economically viable production …

Technological advances in the field of life sciences have led to discovery of organisms that
live in harsh environmental conditions referred to as extremophiles. These organisms have …

Background Fluorescent reporter proteins (FP) have become an indispensable tool for the
optimization of microbial cell factories and in synthetic biology per se. The applicability of the …

The use of gas fermentation for production of chemicals and fuels with lower environmental
impact is a technology that is gaining increasing attention. Over 38 Gt of CO 2 is annually …