Migration is a polarized cellular process that opposes a protrusive front edge to a retracting
trailing edge. From the front to the rear, actin-mediated forces sequentially promote cell …

Neuronal migration is, along with axon guidance, one of the fundamental mechanisms
underlying the wiring of the brain. As other organs, the nervous system has acquired the …

The correct positioning of neurons during development—achieved through directed
migration—is the basis for proper brain function. Several decades of research have yielded …

Actin is a versatile and ubiquitous cytoskeletal protein that plays a major role in both the
establishment and the maintenance of neuronal polarity. For a long time, the most prominent …

Reelin, an extracellular protein essential for neural migration and lamination, is also
expressed in the adult brain. To unravel the function of this protein in the adult forebrain, we …

Reelin is an extracellular matrix protein with various functions during development and in
the mature brain. It activates different signaling cascades in target cells, one of which is the …

Reelin is a glycoprotein that is essential for the correct cytoarchitectonic organization of the
developing CNS. Its function in the adult brain is less understood, although it has been …

Glycogen synthase kinase‐3 (GSK‐3) unique position in modulating the function of a
diverse series of proteins in combination with its association with a wide variety of human …

GSK3 has diverse functions, including an important role in brain pathology. In this paper, we
address the primary functions of GSK3 in development and neuroplasticity, which appear to …

The morphology of cells is key to their function. Neurons extend a long axon and several
shorter dendrites to transmit signals in the nervous system. This process of neuronal …