Abstract Obsessive-Compulsive Disorder (OCD) is a prevalent and severe clinical condition whose hallmarks are excessive, unwanted thoughts (obsessions) and repetitive behaviors …
E Voyiaziakis, O Evgrafov, D Li, HJ Yoon… - Molecular …, 2011 - nature.com
Genetic association studies of SLC6A4 (SERT) and obsessive-compulsive disorder (OCD) have been equivocal. We genotyped 1241 individuals in 278 pedigrees from the OCD …
K Haddley, AS Vasiliou, FR Ali, UM Paredes… - Neurochemical …, 2008 - Springer
We have demonstrated in both the human serotonin transporter gene (5HTT) and the dopamine transporter gene (DAT1) that specific polymorphic variants termed Variable …
C Binelli, A Muñiz, S Sanches, A Ortiz… - European …, 2015 - cambridge.org
Purpose: To study qualitatively different subgroups of social anxiety disorder (SAD) based on harm avoidance (HA) and novelty seeking (NS) dimensions. Method: One hundred and …
PA Saiz, MP Garcia-Portilla, C Arango… - Progress in Neuro …, 2008 - Elsevier
BACKGROUND: To date, research examining the relationship between serotonergic genes and obsessive–compulsive disorder (OCD) has yielded conflicting results. The purpose of …
Objective Impaired inhibition may perpetuate repetitive symptoms in obsessive-compulsive disorder (OCD), however OCD-specific deficits have yet to be established. We investigated …
K Haddley, VJ Bubb, G Breen… - Behavioral …, 2012 - Springer
The serotonin transporter is a key regulator of the bioavailability of serotonin and therefore any modulation in the expression or action of the transporter would be expected to have …
D Rigoni, S Pellegrini, V Mariotti, A Cozza… - Frontiers in behavioral …, 2010 - frontiersin.org
Despite the advances in the understanding of neural and genetic foundations of violence, the investigation of the biological bases of a mental disorder is rarely included in psychiatric …
Abstract Background Obsessive-Compulsive Disorder (OCD) is a complex and chronic disorder characterized by recurrent thoughts and/or repetitive behaviors. Given the potent …