Pseudomonas aeruginosa is an important opportunistic pathogen responsible for the cause
of acute lung injury and acute respiratory distress syndrome. P. aeruginosa isthe leading …

The regenerative capacity of lung and liver is sometimes impaired by chronic or
overwhelming injury. Orthotopic transplantation of parenchymal stem cells to damaged …

MORF4-related gene on chromosome 15 (MRG15), a chromatin remodeller, is evolutionally
conserved and ubiquitously expressed in mammalian tissues and cells. MRG15 plays vital …

Background & Aims How hepatic steatosis progresses to non-alcoholic steatohepatitis
(NASH) is complicated and remains unclear. The mortality factor 4-like protein 1 (MORF4L1 …

Acute lung injury (ALI) is characterized by tissue damage and inflammatory cytokine
secretion; however, the therapeutic options available to treat ALI remain limited. Necrostatin …

Abstract Interleukin-3 (IL-3) receptor α (IL-3Rα) is the α subunit of the ligand-specific IL-3R
and initiates intracellular signaling in response to IL-3. IL-3 amplifies proinflammatory …

Post-translational modifications (PTM) such as methylation, acetylation, phosphorylation,
and ubiquitination of histones and other proteins regulate expression of genes. The …

The rhythmic regulation of transcriptional processes is intimately linked to lipid homeostasis,
to anticipate daily changes in energy access. The Rev-erbα–HDAC3 complex was …

ABSTRACT E3 ubiquitin ligase recognizes its protein substrates via specific molecular
signatures for ubiquitin proteasomal degradation. However, the role of acetylation …

Pseudomonas aeruginosa induced acute lung injury is such a serious risk to public health,
but the pathological regulation remains unclear. Here, we reported that PA mediated …