Active iodide (I−) transport in both the thyroid and some extrathyroidal tissues is mediated by
the Na+/I− symporter (NIS). In the thyroid, NIS-mediated I− uptake plays a pivotal role in …

Abstract The Na+/I− symporter (NIS) is the plasma membrane glycoprotein that mediates
active I− transport in the thyroid and other tissues, such as salivary glands, stomach …

Human milk is considered the optimal nutrition for infants as it provides additional attributes
other than nutritional support for the infant and contributes to the mother's health as well …

Iodide Handling Disorders lead to defects of the biosynthesis of thyroid hormones (thyroid
dyshormonogenesis, TD) and thereafter congenital hypothyroidism (CH), the most common …

The sodium/iodide symporter (NIS or SLC5A5) is an intrinsic membrane protein implicated
in iodide uptake into thyroid follicular cells. It plays a crucial role in iodine metabolism and …

In the beginning (before the genomic revolution) thyroid disorders were primarily diagnosed
by the presence of a goiter and thought to be due to either deficiency or excess of iodine …

The human sodium iodide symporter (hNIS) is a theranostic reporter gene which
concentrates several clinically approved SPECT and PET radiotracers and plays an …

Background: Considering the high prevalence of congenital hypothyroidism (CH) in Isfahan
and its different etiologies in comparison with other countries, the high rate of parental …

Натрий-йод симпортёр (NIS) трансмембранный белок, участвующий в поглощении
йодида в фолликулярных клетках щитовидной железы. Он играет критическую роль в …

Background: Iodide transport defect (ITD) is an infrequent condition associated with
congenital dyshormonogenetic goiter due to mutations in the Na+/I− symporter (NIS) gene …