Novel signatures of prostate cancer progression and therapeutic resistance

J Wang, R Ben-David, R Mehrazin… - Expert Opinion on …, 2023 - Taylor & Francis
Introduction The extensive heterogeneity of prostate cancer (PCa) and multilayered
complexity of progression to castration-resistant prostate cancer (CRPC) have contributed to …

Novel combinatorial approaches to tackle the immunosuppressive microenvironment of prostate cancer

EG Shackleton, HY Ali, M Khan, GA Pockley… - Cancers, 2021 - mdpi.com
Simple Summary The mainstay of treatment for advanced prostate cancer (PCa) is androgen
deprivation therapy (ADT), and although patients initially respond, almost all will eventually …

ExoDx prostate test as a predictor of outcomes of high-grade prostate cancer–an interim analysis

R Tutrone, B Lowentritt, B Neuman… - Prostate Cancer and …, 2023 - nature.com
Background Patient outcomes were assessed based on a pre-biopsy ExoDx Prostate (EPI)
score at 2.5 years of the 5-year follow-up of ongoing prostate biopsy Decision Impact Trial of …

PSMA Expression Predicts Early Biochemical Response in Patients with Metastatic Castration-Resistant Prostate Cancer under 177Lu-PSMA-617 Radioligand …

L Widjaja, RA Werner, TL Ross, FM Bengel, T Derlin - Cancers, 2021 - mdpi.com
Simple Summary Prostate-specific membrane antigen (PSMA) is a promising target for both
imaging and radioligand therapies (RLT) for men with prostate cancer. However, not all …

Risk subtyping and prognostic assessment of prostate cancer based on consensus genes

J Meng, Y Guan, B Wang, L Chen, J Chen… - Communications …, 2022 - nature.com
Prostate cancer (PCa) is the most frequent malignancy in male urogenital system around
worldwide. We performed molecular subtyping and prognostic assessment based on …

Prostate cancer aggressive prediction: preponderant diagnostic performances of intravoxel incoherent motion (IVIM) imaging and diffusion kurtosis imaging (DKI) …

Y Shan, X Chen, K Liu, M Zeng, J Zhou - Abdominal Radiology, 2019 - Springer
Purpose To explore the preponderant diagnostic performances of IVIM and DKI in predicting
the Gleason score (GS) of prostate cancer. Methods Diffusion-weighted imaging data were …

Development of a glycoproteomic strategy to detect more aggressive prostate cancer using lectin-immunoassays for serum fucosylated PSA

C Wang, N Höti, TSM Lih, LJ Sokoll, R Zhang… - Clinical Proteomics, 2019 - Springer
Background Prostate-specific antigen (PSA) is commonly used as a serum biomarker for the
detection of prostate cancer. However, levels of PSA in serum do not reliably distinguish …

Computational pathology for precision diagnosis, treatment, and prognosis of cancer

J Cheng, K Huang, J Xu - Frontiers in Medicine, 2023 - frontiersin.org
Histopathology is considered the gold standard in determining the presence and nature of
tumors. Technological advances in automated high-speed and high-resolution wholeslide …

COMMD3:BMI1 Fusion and COMMD3 Protein Regulate C-MYC Transcription: Novel Therapeutic Target for Metastatic Prostate Cancer

S Umbreen, MM Banday, A Jamroze, AP Mansini… - Molecular Cancer …, 2019 - AACR
Gene rearrangement is reported to be associated to the aggressive phenotype and poor
prognosis in prostate cancer. We identified a gene fusion between a transcription repressor …

The value of synthetic magnetic resonance imaging in the diagnosis and assessment of prostate cancer aggressiveness

Z Gao, X Xu, H Sun, T Li, W Ding… - … Imaging in Medicine …, 2024 - pmc.ncbi.nlm.nih.gov
Background Synthetic magnetic resonance imaging (SyMRI) is a fast, standardized, and
robust novel quantitative technique that has the potential to circumvent the subjectivity of …