The maternal gut microbiome in pregnancy: implications for the developing immune system

O Koren, L Konnikova, P Brodin, IU Mysorekar… - Nature Reviews …, 2024 - nature.com
The gut microbiome has important roles in host metabolism and immunity, and microbial
dysbiosis affects human physiology and health. Maternal immunity and microbial …

Role of zinc in neonatal growth and brain growth: review and scoping review

LP Brion, R Heyne, CS Lair - Pediatric Research, 2021 - nature.com
This manuscript includes (1) a narrative review of Zinc as an essential nutrient for fetal and
neonatal growth and brain growth and development and (2) a scoping review of studies …

The maternal serum metabolome by multisegment injection-capillary electrophoresis-mass spectrometry: a high-throughput platform and standardized data workflow …

M Shanmuganathan, Z Kroezen, B Gill, S Azab… - Nature …, 2021 - nature.com
A standardized data workflow is described for large-scale serum metabolomic studies using
multisegment injection-capillary electrophoresis-mass spectrometry. Multiplexed …

Capture and metabolomic analysis of the human endometrial epithelial organoid secretome

CA Simintiras, P Dhakal, C Ranjit… - Proceedings of the …, 2021 - National Acad Sciences
Suboptimal uterine fluid (UF) composition can lead to pregnancy loss and likely contributes
to offspring susceptibility to chronic adult-onset disorders. However, our understanding of …

Associations between the maternal exposome and metabolome during pregnancy

M Chen, Y Guan, R Huang, J Duan… - Environmental …, 2022 - ehp.niehs.nih.gov
Background: Maternal exposure to environmental chemicals during pregnancy can
influence various maternal and offspring health parameters. Modification of maternal …

Identification of biomarkers for preeclampsia based on metabolomics

M Yao, Y Xiao, Z Yang, W Ge, F Liang, H Teng… - Clinical …, 2022 - Taylor & Francis
Background Preeclampsia (PE) is a significant cause of maternal and neonatal morbidity
and mortality worldwide. However, the pathogenesis of PE is unclear and reliable early …

How could metabolomics change pediatric health?

F Bardanzellu, V Fanos - Italian Journal of Pediatrics, 2020 - Springer
In the last years,'omics' technologies, and especially metabolomics, emerged as expanding
scientific disciplines and promising technologies in the characterization of several …

The exploration of fetal growth restriction based on metabolomics: a systematic review

M Yao, Z Yang, X Rong, X Hu, N Yao, M Zhu, X Wang… - Metabolites, 2022 - mdpi.com
Fetal growth restriction (FGR) is a common complication of pregnancy and a significant
cause of neonatal morbidity and mortality. The adverse effects of FGR can last throughout …

Intranasal administration of induced pluripotent stem cell-derived cortical neural stem cell-secretome as a treatment option for Alzheimer's disease

H Mo, J Kim, JY Kim, JW Kim, H Han, SH Choi… - Translational …, 2023 - Springer
Background Alzheimer's disease (AD) is the most common neurodegenerative disorder in
the elderly, resulting in gradual destruction of cognitive abilities. Research on the …

Sex affects human premature neonates' blood metabolome according to gestational age, parenteral nutrition, and caffeine treatment

M Caterino, M Ruoppolo, M Costanzo, L Albano… - Metabolites, 2021 - mdpi.com
Prematurity is the leading cause of neonatal deaths and high economic costs; it depends on
numerous biological and social factors, and is highly prevalent in males. Several factors can …