Application of inductively coupled plasma mass spectrometry in the quantitative analysis of biomolecules with exogenous tags: a review
Inductively coupled plasma mass spectrometry (ICP-MS) with the merits of high sensitivity
and accuracy, strong tolerance to interference and multi-element simultaneous detection …
and accuracy, strong tolerance to interference and multi-element simultaneous detection …
Understanding the relationship between viral infections and trace elements from a metallomics perspective: implications for COVID-19
JR de Jesus, T de Araújo Andrade - Metallomics, 2020 - academic.oup.com
Abstract Recently, the World Health Organization (WHO) declared a pandemic situation due
to a new viral infection (COVID-19) caused by a novel virus (Sars-CoV-2). COVID-19 is …
to a new viral infection (COVID-19) caused by a novel virus (Sars-CoV-2). COVID-19 is …
Antimicrobial photodynamic activity of gallium-substituted haemoglobin on silver nanoparticles
AV Morales-de-Echegaray, L Lin, B Sivasubramaniam… - Nanoscale, 2020 - pubs.rsc.org
Methicillin-resistant Staphylococcus aureus (MRSA), a major scourge in skin and soft-tissue
infections, expresses surface-bound haemoprotein receptors that can be exploited for the …
infections, expresses surface-bound haemoprotein receptors that can be exploited for the …
Exploiting His-Tags for Absolute Quantitation of Exogenous Recombinant Proteins in Biological Matrices: Ruthenium as a Protein Tracer
Metal labeling and ICP MS detection offer an alternative to commonly accepted techniques
that are currently used to quantitate exogenous proteins in vivo, but modifying the protein …
that are currently used to quantitate exogenous proteins in vivo, but modifying the protein …
Ruthenium coordination preferences in imidazole‐containing systems revealed by electrospray ionization mass spectrometry and molecular modeling: Possible cues …
IA Kaltashov, A El Khoury, C Ren… - Journal of Mass …, 2020 - Wiley Online Library
Ruthenium is a platinoid that exhibits a range of unique chemical properties in solution,
which are exploited in a variety of applications, including luminescent probes, anticancer …
which are exploited in a variety of applications, including luminescent probes, anticancer …
In Vitro Functional Quality Characterization of NOTA-Modified Somatropins
N Bracke, H Yao, E Wynendaele, F Verbeke… - Analytical …, 2017 - ACS Publications
Chemical modifications on protein biopharmaceuticals introduce extra variability in addition
to their inherent complexity, hence require more comprehensive analytical and functional …
to their inherent complexity, hence require more comprehensive analytical and functional …
The terminal heme synthetic enzyme, Coproheme Decarboxylase, coordinates heme synthesis and uptake in response to iron in Mycobacteria
RK Donegan, J Copeland, S Edgha, G Brown, OF Hale… - bioRxiv, 2021 - biorxiv.org
Heme is both an essential cofactor and an abundant source of nutritional iron for the human
pathogen Mycobacterium tuberculosis (Mtb). While heme is required for Mtb survival and …
pathogen Mycobacterium tuberculosis (Mtb). While heme is required for Mtb survival and …
Overcoming the Hydrolytic Lability of a Reaction Intermediate in Production of Protein/Drug Conjugates: Conjugation of an Acyclic Nucleoside Phosphonate to a …
S Xu, IA Kaltashov - Molecular Pharmaceutics, 2017 - ACS Publications
Acquired immunodeficiency syndrome (AIDS) remains one of the most serious public health
challenges and a significant cause of mortality for certain populations. Despite the large …
challenges and a significant cause of mortality for certain populations. Despite the large …
Analytical Methods to Support Design and Optimization of Protein Drug Conjugate: Focusing on Haptoglobin-hemoglobin Complex as a Drug Carrier
S Xu - 2017 - scholarworks.umass.edu
Acquired immunodeficiency syndrome (AIDS) remains one of the most serious public health
challenges and a significant cause of mortality for certain populations. Despite the large …
challenges and a significant cause of mortality for certain populations. Despite the large …
CHARACTERIZATION OF BIODISTRIBUTION OF TRANSFERRIN AND RECEPTOR BINDING MECHANISM BY MASS SPECTROMETRY
H Zhao - 2020 - scholarworks.umass.edu
Protein-based therapeutics have emerged as a key driver of rapid growth in drug
development pipelines. However, developing such protein drugs is not straightforward in …
development pipelines. However, developing such protein drugs is not straightforward in …