Hydrocarbons are abundant in anoxic environments and pose biochemical challenges to
their anaerobic degradation by microorganisms. Within the framework of the Priority …

The steroid superfamily includes a wide range of compounds that are essential for living
organisms of the animal and plant kingdoms. Structural modifications of steroids highly affect …

Anaerobic methane oxidation exerts a key control on greenhouse gas emissions, yet factors
that modulate the activity of microorganisms performing this function remain poorly …

The anaerobic formation and oxidation of methane involve unique enzymatic mechanisms
and cofactors, all of which are believed to be specific for C1-compounds. Here we show that …

Enzymatic hydroxylation of activated and nonactivated sp3-carbons attracts keen interest
from the chemistry community as it is one of the most challenging tasks in organic synthesis …

The challenge of activating inert C–H bonds motivates a study of catalysts that draws from
what can be accomplished by natural enzymes and translates these advantageous features …

Highlights•Several enzymatic hydrocarbon activation mechanisms can be identified by ME-
CSIA.•Anaerobic activation reactions are generally linked to high hydrogen …

Ergothioneine is a histidine derivative with a 2-mercaptoimidazole side chain and a
trimethylated α-amino group. Although the physiological function of this natural product is …

Benzene mineralization under nitrate-reducing conditions was successfully established in
an on-site reactor continuously fed with nitrate and sulfidic, benzene-containing …

Despite being a remarkably biodiverse taxon, the class Deltaproteobacteria includes
relatively few model hydrocarbonoclastic isolates. These organisms as well as notable …