Wnt signaling is a highly conserved signaling pathway that plays a critical role in controlling
embryonic and organ development, as well as cancer progression. Genome-wide …

The majority of breast cancers express the estrogen receptor (ERα) and agents targeting this
pathway represent the main treatment modality. Endocrine therapy has proven successful in …

Wnt signaling regulates a variety of cellular processes, including cell fate, differentiation,
proliferation and stem cell pluripotency. Aberrant Wnt signaling is a hallmark of many …

E‐Cadherin/β‐catenin complex plays an important role in maintaining epithelial integrity and
disrupting this complex affect not only the adhesive repertoire of a cell, but also the Wnt …

Simple Summary Drug resistance is prevalent in many types of cancer and decreases
patient survival. The taxanes are anti-mitotic chemotherapeutic agents, widely used since …

The mechanical properties of cells are important in tissue homeostasis and enable cell
growth, division, migration and the epithelial-mesenchymal transition. Mechanical properties …

Purpose: Metaplastic breast carcinoma (MBC) is a rare and aggressive histologic type of
breast cancer, predominantly of triple-negative phenotype, and characterized by the …

Objective The mechanisms of cancer metastasis have been intensely studied recently and
may provide vital therapeutic targets for metastasis prevention. We sought to review the …

Tumor recurrence and metastasis result in an unfavorable prognosis for cancer patients.
Recent studies have suggested that specific microRNAs (miRNAs) may play important roles …

Stromal cell-derived factor 1 (SDF-1) and its receptor, CXCR4, play an important role in
angiogenesis and are associated with tumor progression. This study aimed to investigate …