The immunopathophysiology of endometriosis
Endometriosis is a chronic, inflammatory, estrogen-dependent disease characterized by the
growth of endometrial tissue outside of the uterine cavity. Although the etiology of …
growth of endometrial tissue outside of the uterine cavity. Although the etiology of …
Pharmaceuticals targeting signaling pathways of endometriosis as potential new medical treatment: A review
Endometriosis (EM) is defined as endometrial tissues found outside the uterus. Growth and
development of endometriotic cells in ectopic sites can be promoted via multiple pathways …
development of endometriotic cells in ectopic sites can be promoted via multiple pathways …
Endometriosis, a disease of the macrophage
A Capobianco, P Rovere-Querini - Frontiers in immunology, 2013 - frontiersin.org
Endometriosis, a common cause of pelvic pain and female infertility, depends on the growth
of vascularized endometrial tissue at ectopic sites. Endometrial fragments reach the …
of vascularized endometrial tissue at ectopic sites. Endometrial fragments reach the …
Macrophages are alternatively activated in patients with endometriosis and required for growth and vascularization of lesions in a mouse model of disease
The mechanisms that sustain endometrial tissues at ectopic sites in patients with
endometriosis are poorly understood. Various leukocytes, including macrophages, infiltrate …
endometriosis are poorly understood. Various leukocytes, including macrophages, infiltrate …
Mitochondrial dysfunction and redox imbalance as a diagnostic marker of “free radical diseases”
E Georgieva, D Ivanova, Z Zhelev… - Anticancer …, 2017 - ar.iiarjournals.org
The intracellular redox balance (redox status) is a dynamic system that may change via
many factors. Mitochondria are one of the most important among them. These organelles are …
many factors. Mitochondria are one of the most important among them. These organelles are …
The role of microRNAs in endometriosis and associated reproductive conditions
EMC Ohlsson Teague, CG Print… - Human reproduction …, 2010 - academic.oup.com
BACKGROUND microRNAs (miRNAs) are short, single-stranded RNAs that regulate gene
expression at the post-transcriptional level. Recent research has shown that miRNAs and …
expression at the post-transcriptional level. Recent research has shown that miRNAs and …
The miRNA mirage: how close are we to finding a non-invasive diagnostic biomarker in endometriosis? A systematic review
Background: Endometriosis is a common disorder of the reproductive age group,
characterised by the presence of ectopic endometrial tissue. The disease not only causes …
characterised by the presence of ectopic endometrial tissue. The disease not only causes …
Plasma miR-17-5p, miR-20a and miR-22 are down-regulated in women with endometriosis
S Jia, Y Yang, J Lang, P Sun, J Leng - Human reproduction, 2013 - academic.oup.com
Abstract STUDY QUESTION Can plasma microRNAs be used as a non-invasive diagnostic
test for the detection of endometriosis? SUMMARY ANSWER Plasma miR-17-5p, miR-20a …
test for the detection of endometriosis? SUMMARY ANSWER Plasma miR-17-5p, miR-20a …
[HTML][HTML] Pharmacologic therapies in endometriosis: a systematic review
SR Soares, A Martínez-Varea, JJ Hidalgo-Mora… - Fertility and sterility, 2012 - Elsevier
To assess the literature on preclinical and clinical efficacy and safety data of pharmacologic
groups proposed in the treatment of endometriosis, we performed a systematic review of …
groups proposed in the treatment of endometriosis, we performed a systematic review of …
Angiogenesis and endometriosis
A comprehensive review was performed to survey the role of angiogenesis in the
pathogenesis of endometriosis. This is a multifactorial disease in which the development …
pathogenesis of endometriosis. This is a multifactorial disease in which the development …