Causes, consequences, and treatment of metabolically unhealthy fat distribution

N Stefan - The lancet Diabetes & endocrinology, 2020 - thelancet.com
An increase in fat mass is considered to be an important risk factor for the worldwide
increase in type 2 diabetes and cardiovascular disease. However, for a given fat mass, there …

[HTML][HTML] Causes, characteristics, and consequences of metabolically unhealthy normal weight in humans

N Stefan, F Schick, HU Häring - Cell metabolism, 2017 - cell.com
A BMI in the normal range associates with a decreased risk of cardiometabolic disease and
all-cause mortality. However, not all subjects in this BMI range have this low risk. Compared …

Cardiovascular risk and body-fat abnormalities in HIV-infected adults

S Grinspoon, A Carr - New England Journal of Medicine, 2005 - Mass Medical Soc
Metabolic complications such as dyslipidemia, insulin resistance, and altered fat distribution
(loss of subcutaneous fat and relatively increased central fat) are common in adults infected …

Efficacy and safety of tenofovir DF vs stavudine in combination therapy in antiretroviral-naive patients: a 3-year randomized trial

JE Gallant, S Staszewski, AL Pozniak, E DeJesus… - Jama, 2004 - jamanetwork.com
ContextTenofovir disoproxil fumarate (DF) is a once-daily nucleotide analogue reverse
transcriptase inhibitor. ObjectiveTo evaluate the efficacy and safety of tenofovir DF …

Lipodystrophy: pathophysiology and advances in treatment

CG Fiorenza, SH Chou, CS Mantzoros - Nature Reviews Endocrinology, 2011 - nature.com
Lipodystrophy is a medical condition characterized by complete or partial loss of adipose
tissue. Not infrequently, lipodystrophy occurs in combination with pathological accumulation …

Understanding diabetes in patients with HIV/AIDS

S Kalra, B Kalra, N Agrawal… - Diabetology & metabolic …, 2011 - Springer
This paper reviews the incidence, pathogenetic mechanisms and management strategies of
diabetes mellitus in patients with human immunodeficiency virus (HIV) and acquired …

The official positions of the International Society for Clinical Densitometry: indications of use and reporting of DXA for body composition

DL Kendler, JLC Borges, RA Fielding, A Itabashi… - Journal of Clinical …, 2013 - Elsevier
The technique of body composition by dual-energy X-ray absorptiometry (DXA) has been
used for several years in the research environment. Its ability to accurately and precisely …

Current concepts in the diagnosis and management of metabolic complications of HIV infection and its therapy

DA Wohl, G McComsey, P Tebas… - Clinical Infectious …, 2006 - academic.oup.com
Abstract Changes in fat distribution, dyslipidemia, disordered glucose metabolism, and lactic
acidosis have emerged as significant challenges to the treatment of human …

Plasma metabolomics identifies lipid abnormalities linked to markers of inflammation, microbial translocation, and hepatic function in HIV patients receiving protease …

E Cassol, V Misra, A Holman, A Kamat… - BMC infectious …, 2013 - Springer
Background Metabolic abnormalities are common in HIV-infected individuals on
antiretroviral therapy (ART), but the biochemical details and underlying mechanisms of …

Introduction to the metabolic syndrome

G Alberti - European Heart Journal Supplements, 2005 - academic.oup.com
The metabolic syndrome has its origins in 1923 when Kylin1 described a syndrome
involving hypertension, hyperglycaemia and hyperuricaemia. In the 1940s Vague2 wrote …