Regulation of and challenges in targeting NAD+ metabolism

ME Migaud, M Ziegler, JA Baur - Nature Reviews Molecular Cell …, 2024 - nature.com
Nicotinamide adenine dinucleotide, in its oxidized (NAD+) and reduced (NADH) forms, is a
reduction–oxidation (redox) co-factor and substrate for signalling enzymes that have …

Extracellular NAD+ response to post-hepatectomy liver failure: bridging preclinical and clinical findings

C Kamali, P Brunnbauer, K Kamali, AHA Saqr… - Communications …, 2024 - nature.com
Liver fibrosis progressing to cirrhosis is a major risk factor for liver cancer, impacting surgical
treatment and survival. Our study focuses on the role of extracellular nicotinamide adenine …

Conditional Cell Penetration of Masked CPPs by an ADEPT-like Approach

S Hofmann, C Dombrowsky, D Happel… - ACS Chemical …, 2024 - ACS Publications
The intracellular delivery of cargos via cell penetrating peptides (CPPs) holds significant
promise as a drug delivery vehicle, but a major issue is their lack of cell type specificity …

Fungicidal Activity of Novel 6-Isothiazol-5-ylpyrimidin-4-amine-Containing Compounds Targeting Complex I Reduced Nicotinamide Adenine Dinucleotide …

K Li, Y Lv, R Wu, Z Yu, Y Liang, Z Yu… - Journal of Agricultural …, 2024 - ACS Publications
To discover novel inhibitors of the complex I reduced nicotinamide adenine dinucleotide
(NADH) oxidoreductase as fungicides, a series of 6-isothiazol-5-ylpyrimidin-4-amine …

Tandem mass tag-based quantitative proteomics elucidates the inactivation mechanisms of high-power pulsed microwave treatment on Pseudomonas aeruginosa …

AP Bassey, Y Zhang, Y Zhu, X Cui, X Zhang… - Innovative Food Science …, 2024 - Elsevier
This study explored the effect of HPPM treatment (200 Hz for 3, 5, 7, 9, and 11 min) on P.
aeruginosa PAO1 inactivation using tandem mass tag-based quantitative proteomics. HPPM …

A Simple, Fast, Sensitive LC-MS/MS Method to Quantify NAD (H) in Biological Samples: Plasma NAD (H) Measurement to Monitor Brain Pathophysiology

T Ishima, N Kimura, M Kobayashi, R Nagai… - International Journal of …, 2024 - mdpi.com
Nicotinamide adenine dinucleotide (NAD) is a cofactor in redox reactions and an essential
mediator of energy metabolism. The redox balance between NAD+ and NADH affects …

Optimized protocol for quantification of extracellular nicotinamide adenine dinucleotide: evaluating clinical parameters and pre-analytical factors for translational …

AHA Saqr, C Kamali, P Brunnbauer, N Haep… - Frontiers in …, 2024 - frontiersin.org
Nicotinamide adenine dinucleotide (NAD+), a coenzyme for more than 500 enzymes, plays
a central role in energy production, metabolism, cellular signaling, and DNA repair. Until …

核磁共振波谱法同时定量测定保健品中烟酰胺腺嘌呤二核苷酸及其前体化合物.

张佳琳, 范春林, 张紫娟 - Journal of Food Safety & Quality, 2023 - search.ebscohost.com
核磁共振波谱法同时定量测定保健品中烟酰胺腺嘌呤二核苷酸及其前体化合物 Page 1 第14 卷第
24 期 食品安全质量检测学报 Vol. 14 No. 24 2023 年12 月 Journal of Food Safety and Quality …

Redox homeostasis and pH monitoring: a step forward to personalized medicine and dermatology

T Lotti, H Kocic, KM Lomonosov - Journal of Applied …, 2024 - scientificeditorial.com
Skin is continually subjected to various environmental stressors, such as pollution, UV rays,
and other oxidative damage factors. It is obligatory to ascertain the exact importance of …