The observation that long tracts of RNA are associated with replicating molecules of
mitochondrial DNA (mtDNA) suggests that the mitochondrial genome of mammals is copied …

Aminobiphenyl, a known carcinogen, has many environmental sources like cigarette smoke,
industrial waste, and so forth. It can be metabolized to form a potent mutagen, N‐hydroxy‐N …

Nitric oxide (NO) generated by the reduction of sodium nitrite with sodium dithionite caused
damage to plasmid Bluescript DNA leading to strand breaks and base modifications. The …

DNA damage is one of the leading causes of various pathological conditions including
carcinogenesis. Crotonaldehyde is a 4-carbon unsaturated bifunctional aldehyde which is …

DNA damage plays an important role in mutagenesis, carcinogenesis, aging and several
other pathophysiological conditions. Crotonaldehyde is a four carbon unsaturated …

Hydroxyl radical, generated by UV irradiation of hydrogen peroxide caused damage to
native calf thymus DNA leading to strand breaks, base modification and decrease in melting …

The formation of reactive oxygen species (ROS), although a normal cellular activity, is
considerably enhanced under chronic inflammatory conditions and ischemia. These species …

The present study was designed to probe the possible role of singlet oxygen and superoxide
anion radical modified DNA in the etiopathogenesis of Systemic lupus erythematosus …

Studies have been carried out to synthesize and characterize the photoconjugates between
positively charged amino acids (lysine and arginine) and the polydeoxyribonucleotide C …

The effect of hydroxyl radicals on polyinosinic acid [poly (I)] was studied. Strand breaks,
base alteration and a decrease in absorbance at 248 nm (λmax) were observed upon• OH …