Erectile dysfunction and diabetes: A melting pot of circumstances and treatments

G Defeudis, R Mazzilli, M Tenuta… - Diabetes/metabolism …, 2022 - Wiley Online Library
Diabetes mellitus (DM), a chronic metabolic disease characterised by elevated levels of
blood glucose, is among the most common chronic diseases. The incidence and prevalence …

Effects of diet and antihyperglycemic drugs on erectile dysfunction: A systematic review

G Defeudis, R Mazzilli, AM Di Tommaso… - …, 2023 - Wiley Online Library
Background Erectile dysfunction is recognized as one of the complications of diabetes
mellitus. To date, a wide gap of knowledge is present on the efficacy of pharmacological …

Role of glucose-lowering medications in erectile dysfunction

A Cignarelli, VA Genchi, R D'Oria, F Giordano… - Journal of clinical …, 2021 - mdpi.com
Erectile dysfunction (ED) is a long-term complication of type 2 diabetes (T2D) widely known
to affect the quality of life. Several aspects of altered metabolism in individuals with T2D may …

Repurposing small molecules to target PPAR-γ as new therapies for peripheral nerve injuries

MLD Rayner, J Healy, JB Phillips - Biomolecules, 2021 - mdpi.com
The slow rate of neuronal regeneration that follows peripheral nerve repair results in poor
recovery, particularly where reinnervation of muscles is delayed, leading to atrophy and …

Insulin-like growth factor-1–loaded polymeric poly (lactic-co-glycolic) acid microspheres improved erectile function in a rat model of bilateral cavernous nerve injury

NM Haney, S Talwar, PK Akula… - The Journal of …, 2019 - academic.oup.com
Background Previous studies have documented improvement in erectile function after
bilateral cavernous nerve injury (BCNI) in rats with the use of pioglitazone. Our group …

The effect of cavernous nerve traction on erectile function in rats

H Li, L Chen, T Wang, S Wang, J Liu - PLoS One, 2017 - journals.plos.org
We performed this study to evaluate the effect of cavernous nerve (CN) traction on erectile
function in rats. Thirty-two 8-week-old Sprague–Dawley rats were divided into four groups …

Pioglitazone's beneficial effects on erectile function preservation after cavernosal nerve injury in the rat are negated by inhibition of the insulin-like growth factor-1 …

DJ Heidenberg, NM Haney, BM Rezk… - International Journal of …, 2019 - nature.com
To determine if the insulin-like growth factor-1 (IGF-1) pathway is involved in the
improvement in erectile function recovery in rats after nerve crush injury treated with …

Preventing erectile dysfunction after radical prostatectomy: Nerve-sparing techniques, penile rehabilitation, and novel regenerative therapies

M Whalen - by T. Genadiev. London: IntechOpen, 2019 - books.google.com
Erectile dysfunction is a known and much-dreaded functional consequence of radical
prostatectomy. Dr. Patrick Walsh pioneered the nerve-sparing radical retropubic …

[PDF][PDF] Adipose Derived Stem Cell Engraftment Improves Erectile Function in a Rat Model of Cavernosal Nerve Injury

JE Anaissie, AG Reddy, B Song, Z Brabadi… - J Regen Med 9: 3. doi …, 2020 - researchgate.net
Abstract Adipose-derived-stem-cells (ADSC) have shown promise in treating erectile
dysfunction (ED). Here we investigated the effect of ADSC engraftment in restoring erectile …

[PDF][PDF] Insulin-Like Growth Factor-1eLoaded Polymeric Poly (Lactic-Co-Glycolic) Acid Microspheres Improved Erectile Function in a Rat Model of Bilateral Cavernous …

GS Pema, TV Ninh, BM Rezk, Z Heidari, MT Bouljihad… - J Sex Med, 2019 - academia.edu
Background: Previous studies have documented improvement in erectile function after
bilateral cavernous nerve injury (BCNI) in rats with the use of pioglitazone. Our group …