The enantioselective synthesis of fluorinated molecules has drawn much attention within the
chemical community due to its unique stereoelectronic properties. The main aim of this …

Synthetic fluorinated compounds are enormously useful in areas such as materials,
agrochemicals, pharmaceuticals and fine chemicals. While methods of electrophilic …

An efficient synthesis of spiropyrazolones based on organocatalysis is described. The
reaction between pyrazolones, enolizable aldehydes and enals is catalyzed by secondary …

A remarkably efficient photosensitizer, N719 dye, was used in asymmetric tandem Michael
addition/oxyamination of aldehydes, rendering α, β-substituted aldehydes in good yields …

Cyclopropane rings are an important structural motif frequently found in many natural
products and pharmaceuticals. Commonly, biocatalytic methodologies for the asymmetric …

We report the first organocatalytic activation of monofluorinated silyl enol ethers 1, by
nucleophilic tertiary amine catalysis, to develop asymmetric reactions for the construction of …

The synthesis of spiro compounds through a Michael–Michael–aldol reaction is reported.
The reaction affords spiropyrazolone derivatives in good yields, in almost diastereo‐and …

The majority of fluorinated pharmaceutical products bear structurally simple fluoro-and
trifluoromethyl-aromatic subunits, in part because of the ready availability of a wide range of …

Traditional procedures toward 2-fluoromalonates tend to meet overfluorination. Herein, we
describe a mild and efficient palladium-catalyzed carbonylative strategy for the synthesis of …

A new, easy, and highly enantioselective method for the synthesis of quaternary α‐alkyl‐α‐
amino acids based on organocatalysis is reported. The addition of oxazolones to 1, 1‐bis …