Existing antibacterial agents can be categorized into two generations, but bacterial
insensitivity towards both of these classes poses a serious public health challenge …

Bacterial infections are increasingly resistant to antimicrobial therapy. Intense research
focus has thus been placed on identifying the mechanisms that bacteria use to resist killing …

Understanding how bactericidal antibiotics kill bacteria remains an open question. Previous
work has proposed that primary drug-target corruption leads to increased energetic …

Bacteria can adapt to stressful conditions through mutations affecting the RNA polymerase
core subunits that lead to beneficial changes in transcription. In response to selection with …

As a major cause of clinical chronic infection, microbial biofilms/microcolonies in host tissues
essentially live in 3D‐constrained microenvironments, which potentially modulate their …

Introduction The escalating prevalence of bacterial resistance, particularly multidrug-
resistant bacteria like Acinetobacter baumannii, has become a significant global public …

This work aimed to evaluate the predatory activity of Bdellovibrio bacteriovorus 109J on
clinical isolates of Pseudomonas aeruginosa selected from well-characterized collections of …

Accurate detection of bacterial antibiotic sensitivity is crucial for theranostics and the
containment of antibiotic-resistant infections. However, the intricate task of detecting and …

Antibiotic therapy alters bacterial abundance and metabolism in the gut microbiome, leading
to dysbiosis and opportunistic infections. Bacteroides thetaiotaomicron (Bth) is both a …

The proton-motive force (PMF), consisting of a pH gradient and a membrane potential (ΔΨ)
underpins many processes essential to bacterial growth and/or survival. Yet bacteria often …