The Eph receptor tyrosine kinases and their ephrin ligands have intriguing expression
patterns in cancer cells and tumour blood vessels, which suggest important roles for their …

Critical roles for EPH receptor (EPH)–ephrin signalling in a range of chronic and
regenerative diseases are increasingly being recognized. In particular, the complex roles of …

Eph receptors and the corresponding Eph receptor-interacting (ephrin) ligands jointly
constitute a critical cell signaling network that has multiple functions. The tyrosine kinase …

Eph receptor tyrosine kinases mould the behaviour of many cell types by binding membrane-
anchored ligands, ephrins, at sites of cell–cell contact. Eph signals affect both of the …

Importance of the field: High mortality rates with cancers warrant further development of
earlier diagnostics and better treatment strategies. Membrane-bound erythropoietin …

Background: Eph receptors and their ligands, the ephrins, represent a large class of cell–cell
communication molecules with well-defined developmental functions. Their role in healthy …

The Eph receptor tyrosine kinases and ephrin ligands have been studied extensively for
their roles in developmental processes. In recent years, Eph receptors and ephrins have …

Eph receptors are the largest receptor tyrosine kinase family of transmembrane proteins with
an extracellular domain capable of recognizing signals from the cells' environment and …

Context.—Metastatic disease is the most critical determinant of resectability of pancreatic
cancer and accounts for the poor outcome of patients with this disease. Thus, a better …

Overexpression of the receptor tyrosine kinase EPH receptor A2 (EphA2) is commonly
observed in aggressive breast cancer and correlates with a poor prognosis. However, while …