Tumor abnormality-oriented nanomedicine design
Anticancer nanomedicines have been proven effective in mitigating the side effects of
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
chemotherapeutic drugs. However, challenges remain in augmenting their therapeutic …
Polymeric nanoparticles for targeted drug delivery system for cancer therapy
F Masood - Materials Science and Engineering: C, 2016 - Elsevier
A targeted delivery system based on the polymeric nanoparticles as a drug carrier
represents a marvelous avenue for cancer therapy. The pivotal characteristics of this system …
represents a marvelous avenue for cancer therapy. The pivotal characteristics of this system …
Cancer nanotechnology: the impact of passive and active targeting in the era of modern cancer biology
Cancer nanotherapeutics are progressing at a steady rate; research and development in the
field has experienced an exponential growth since early 2000's. The path to the …
field has experienced an exponential growth since early 2000's. The path to the …
From sewer to saviour—targeting the lymphatic system to promote drug exposure and activity
The lymphatic system serves an integral role in fluid homeostasis, lipid metabolism and
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …
immune control. In cancer, the lymph nodes that drain solid tumours are a primary site of …
PLGA-based nanoparticles: an overview of biomedical applications
Poly (lactic-co-glycolic acid)(PLGA) is one of the most successfully developed
biodegradable polymers. Among the different polymers developed to formulate polymeric …
biodegradable polymers. Among the different polymers developed to formulate polymeric …
Nanoparticles as drug delivery systems
AZ Wilczewska, K Niemirowicz, KH Markiewicz… - Pharmacological …, 2012 - Elsevier
Controlled drug delivery systems (DDS) have several advantages compared to the
traditional forms of drugs. A drug is transported to the place of action, hence, its influence on …
traditional forms of drugs. A drug is transported to the place of action, hence, its influence on …
Design, functionalization strategies and biomedical applications of targeted biodegradable/biocompatible polymer-based nanocarriers for drug delivery
Design and functionalization strategies for multifunctional nanocarriers (eg, nanoparticles,
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …
micelles, polymersomes) based on biodegradable/biocompatible polymers intended to be …
Engineering nanoparticles to locally activate T cells in the tumor microenvironment
D Wang, T Wang, H Yu, B Feng, L Zhou, F Zhou… - Science …, 2019 - science.org
Immunological tolerance of tumors is characterized by insufficient infiltration of cytotoxic T
lymphocytes (CTLs) and immunosuppressive microenvironment of tumor. Tumor resistance …
lymphocytes (CTLs) and immunosuppressive microenvironment of tumor. Tumor resistance …
Self-assembling peptides and their application in the treatment of diseases
S Lee, THT Trinh, M Yoo, J Shin, H Lee, J Kim… - International journal of …, 2019 - mdpi.com
Self-assembling peptides are biomedical materials with unique structures that are formed in
response to various environmental conditions. Governed by their physicochemical …
response to various environmental conditions. Governed by their physicochemical …
Advanced drug delivery to the lymphatic system: lipid-based nanoformulations
The delivery of drugs and bioactive compounds via the lymphatic system is complex and
dependent on the physiological uniqueness of the system. The lymphatic route plays an …
dependent on the physiological uniqueness of the system. The lymphatic route plays an …