In the last few years, the monounsaturated hexadecenoic fatty acids are being increasingly
considered as biomarkers of health with key functions in physiology and pathophysiology …

The endoplasmic reticulum (ER) is the key organelle for membrane biogenesis. Most lipids
are synthesized in the ER, and most membrane proteins are first inserted into the ER …

The CXC chemokine receptor 4 (CXCR4) in endothelial cells (ECs) and vascular smooth
muscle cells (VSMCs) is crucial for vascular integrity. The atheroprotective functions of …

The biological functions of lipids largely depend on their chemical structures. The position
and configuration of C= C bonds are two of the essential attributes that determine the …

The precise location of CC bonds in bioactive molecules is critical for a deep understanding
of the relationship between their structures and biological roles. However, the traditional …

Residential macrophages in adipose tissue play a pivotal role in the development of
inflammation not only within this tissue, but also affect the proinflammatory status of the …

Background & aims There has been controversial evidence regarding the relationship
between isomers of circulating trans-fatty acids (TFAs) and mortality. This study aimed to …

Adipose tissue is a highly metabolically-active tissue that senses and secretes hormonal
and lipid mediators that facilitate adaptations to metabolic tissues. In recent years, the role of …

Since the early 2010s, dietary trans-palmitoleic acid (trans-9-hexadecenoic acid, trans-9-
C16: 1 in the Δ-nomenclature, trans-C16: 1 n-7 in the Ω-nomenclature, TPA) has been …

Accumulating evidence reveals that adipose tissue is an immunologically active organ that
exerts multiple impacts on the regulation of systemic energy metabolism. Adipose tissue …