Skin cancer: understanding the journey of transformation from conventional to advanced treatment approaches

N Hasan, A Nadaf, M Imran, U Jiba, A Sheikh… - Molecular cancer, 2023 - Springer
Skin cancer is a global threat to the healthcare system and is estimated to incline
tremendously in the next 20 years, if not diagnosed at an early stage. Even though it is …

Advances in cutaneous squamous cell carcinoma

MCG Winge, LN Kellman, K Guo, JY Tang… - Nature Reviews …, 2023 - nature.com
Human malignancies arise predominantly in tissues of epithelial origin, where the stepwise
transformation from healthy epithelium to premalignant dysplasia to invasive neoplasia …

[HTML][HTML] European consensus-based interdisciplinary guideline for invasive cutaneous squamous cell carcinoma: Part 2. Treatment–Update 2023

AJ Stratigos, C Garbe, C Dessinioti, C Lebbe… - European Journal of …, 2023 - Elsevier
In order to update recommendations on treatment, supportive care, education, and follow-up
of patients with invasive cutaneous squamous cell carcinoma (cSCC), a multidisciplinary …

Pristine and alkali and alkaline earth metals encapsulated B36N36 nanoclusters as prospective delivery agents and detectors for 5‐fluorouracil anticancer drug

E Shakerzadeh, KK Zborowski… - Applied …, 2022 - Wiley Online Library
Quantum chemical investigation using density functional theory (DFT) approach is
performed to assess the interactions of the anticancer 5‐fluorouracil (FU) drug and B36N36 …

Clinical Efficacy of 5-Fluorouracil and Bleomycin in Dermatology

S Kim, YR Woo, SH Cho, JD Lee, HS Kim - Journal of Clinical Medicine, 2024 - mdpi.com
Bleomycin and 5-fluorouracil (5-FU) are widely used in various dermatological disorders.
Both drugs are well-recognized as antineoplastic drugs and exert their effect by blocking the …

Synthetic Calcium Silicate Biocomposite Based on Sea Urchin Skeleton for 5-Fluorouracil Cancer Delivery

EK Papynov, OO Shichalin, OV Kapustina, IY Buravlev… - Materials, 2023 - mdpi.com
Synthetic calcium silicates and phosphates are promising compounds for targeted drug
delivery for the effective treatment of cancerous tumors, and for minimizing toxic effects on …

Needle before Scalpel: Considering the Role of Intratumoral Therapy in Melanoma

TH Katz, A Javed, JG Powers - Dermatologic Therapy, 2024 - Wiley Online Library
Advanced melanoma and nonmelanoma skin cancer or cutaneous metastases not
amenable to surgery often require alternate therapy. Although surgery is first‐line treatment …

Non-surgical treatments for keratinocyte carcinomas

KJB Kus, ES Ruiz - Advances in Therapy, 2021 - Springer
Skin cancer is the most common malignancy worldwide, comprising approximately 30% of
all human tumors. In recent decades, the incidence of keratinocyte carcinomas, which …

The contributions of cancer-testis and developmental genes to the pathogenesis of keratinocyte carcinomas

B Ramchatesingh, J Gantchev, A Martínez Villarreal… - Cancers, 2022 - mdpi.com
Simple Summary In addition to mutations, ectopically-expressed genes are emerging as
important contributors to cancer development. Efforts to characterize the expression patterns …

[HTML][HTML] Intralesional Treatments for Invasive Cutaneous Squamous Cell Carcinoma

G Baeza-Hernández, J Cañueto - Cancers, 2023 - mdpi.com
Simple Summary Cutaneous squamous cell carcinoma (cSCC) is the second most frequent
cancer in humans, and it is especially common in fragile, elderly people. Surgery is the …