The AID/APOBEC polynucleotide cytidine deaminases have historically been classified as
either DNA mutators or RNA editors based on their first identified nucleic acid substrate …

The AID/APOBEC family enzymes convert cytosines in single-stranded DNA to uracils,
causing base substitutions and strand breaks. They are induced by cytokines produced …

The APOBEC family of cytidine deaminases has been proposed to represent a major
enzymatic source of mutations in cancer. Here, we summarize available evidence that links …

Apolipoprotein B mRNA-editing enzyme catalytic polypeptide-like (APOBEC) proteins are a
diverse and evolutionarily conserved family of cytidine deaminases that provide a variety of …

Human cancers results in large part from the accumulation of multiple mutations. The
progression of premalignant cells is an evolutionary process in which mutations provide the …

APOBECs (apolipoprotein B mRNA editing enzyme, catalytic polypeptide-like) are a family
of cytidine deaminases that prefer single-stranded nucleic acids as substrates. Besides their …

The APOBEC3 family of human cytidine deaminases is involved in various cellular
processes, including the innate and acquired immune system, mostly through inducing C-to …

The advent of next generation sequencing (NGS) has fostered a shift in basic analytic
strategies of a gene expression analysis in diverse pathologies for the purposes of research …

Simple Summary APOBEC cytosine deaminases represent potent mutational sources in
over 50% of human cancers and are linked to tumor heterogeneity and therapy responses …

Cancer initiates as a consequence of genomic mutations and its subsequent progression
relies in part on increased production of ribosomes to maintain high levels of protein …