Molecular epidemiologic studies of tuberculosis (TB) have focused largely on utilizing
molecular techniques to address short-and long-term epidemiologic questions, such as in …

Background Tuberculosis (TB) transmission often occurs within a household or community,
leading to heterogeneous spatial patterns. However, apparent spatial clustering of TB could …

Several human pathogens (eg, Bacillus anthracis, Yersinia pestis, Bordetella pertussis,
Plasmodium falciparum, and Mycobacterium tuberculosis) have very restricted unselected …

We studied genetic relationships among 5069 Mycobacterium tuberculosis strains
recovered from patients enrolled in 4 population-based studies in the United States and …

Multidrug-resistant tuberculosis (MDR-TB) is a major public health problem because
treatment is complicated, cure rates are well below those for drug-susceptible tuberculosis …

Despite evidence that transmission is driving an extensively drug-resistant TB (XDR-TB)
epidemic, our understanding of where and between whom transmission occurs is limited …

In this study, we determined the genetic diversity of Mycobacterium tuberculosis isolated in
Norway from 1999 to 2001. The results were compared to those for strains isolated from …

It has not been possible to distinguish different strains of Mycobacterium leprae according to
their genetic sequence. However, the genome contains several variable-number tandem …

The use of isobaric tags such as iTRAQ allows the relative and absolute quantification of
hundreds of proteins in a single experiment for up to eight different samples. More classical …

Molecular epidemiology (ME) is one of the main areas in tuberculosis research which is
widely used to study the transmission epidemics and outbreaks of tubercle bacilli. It exploits …