Axons functionally link the somato-dendritic compartment to synaptic terminals. Structurally
and functionally diverse, they accomplish a central role in determining the delays and …

The presence of ionotropic receptors to neurotransmitters in presynaptic structures is well
documented in many synapses of the mammalian brain. However, due to technical …

In many neurons, subthreshold depolarization in the soma can transiently increase action-
potential (AP)-evoked neurotransmission via analog-to-digital facilitation. The mechanisms …

Key points GABAA receptors have been described in the axonal compartment of neurons;
contrary to dendritic GABAA receptors, axonal GABAA receptors usually induce depolarizing …

The brain's control of movement is thought to involve coordinated activity between cerebellar
Purkinje cells. The results reported here demonstrate that somatic Ca 2+ imaging is a faithful …

Axons are equipped with the digital signaling capacity by which they generate and faithfully
propagate action potentials (APs), and also with the analogue signaling capacity by which …

In several types of central mammalian synapses, sustained presynaptic stimulation leads to
a sequence of two components of synaptic vesicle release, reflecting the consecutive …

Clinical Neuroscience offers a comprehensive overview of the biological bases of major
psychological and psychiatric disorders, and provides foundational information regarding …

Analog signaling describes the use of graded voltage changes as signals in the axonal
compartment. Analog signaling has been described originally in invertebrates but more …

Inhibitory interneurons interconnected via electrical and chemical (GABAA receptor)
synapses form extensive circuits in several brain regions. They are thought to be involved in …