Cellular actin networks exhibit a wide range of sizes, shapes, and architectures tailored to
their biological roles. Once assembled, these filamentous networks are either maintained in …

Cells use the actin cytoskeleton for many of their functions, including their division,
adhesion, mechanosensing, endo-and phagocytosis, migration, and invasion. Actin bundles …

During striated muscle development the first periodically repeated units appear in the
premyofibrils, consisting of immature sarcomeres that must undergo a substantial growth …

Cellular actin networks display distinct assembly and disassembly dynamics resulting from
multicomponent reactions occurring primarily at the two ends and the sides of actin filaments …

Spotted fever group Rickettsia undergo actin-based motility inside infected eukaryotic cells
using Sca2 (surface cell antigen 2): an∼ 1800 amino-acid monomeric autotransporter …

Actin bundling proteins crosslink filaments into polarized structures that shape and support
membrane protrusions including filopodia, microvilli, and stereocilia. In the case of epithelial …

Intracellular actin networks assemble through the addition of ATP-actin subunits at the
growing barbed ends of actin filaments. This is followed by “aging” of the filament via ATP …

Competition between bacterial species is a major factor shaping microbial communities. It is
possible but remains largely unexplored that competition between bacterial pathogens can …

Actin is a highly conserved and fundamental protein in eukaryotes and participates in a
broad spectrum of cellular functions. Cells maintain a conserved ratio of actin isoforms, with …

Entry of Salmonella into host enterocytes relies on its pathogenicity island 1 effector SipA.
We found that SipA binds to F-actin in a 1: 2 stoichiometry with sub-nanomolar affinity. A cryo …