The skin is the main barrier between the body and the environment, protecting it from
external oxidative stress induced by ultraviolet rays. It also prevents the entrance of …

Pruritus, the most common cutaneous symptom, is widely seen in many skin complaints. It is
an uncomfortable feeling on the skin and sometimes impairs patients' quality of life. At …

To identify itch-related mediators and receptors that are differentially expressed in pruritic
skin, we used RNA sequencing to analyze the complete transcriptome in skin from paired …

Diabetes mellitus (DM) is a global epidemic with increasing incidence, which results in
diverse complications, seriously affects the patient quality of life, and brings huge economic …

Purpose of review: Uremic pruritus is a highly prevalent and debilitating symptom in patients
with chronic kidney disease (CKD) and end-stage kidney disease (ESKD). The purpose of …

Chronic pruritus (CP) is defined as an unpleasant sensation causing a desire to scratch and
lasting> 6 weeks. It has a multifactorial etiology but is more frequently associated with …

Resveratrol-enriched rice (RR) was developed using genetic engineering to combine the
properties of resveratrol and rice. To evaluate the effect of RR on pruritic skin inflammation in …

Abstract Phosphodiesterase 4 (PDE4) inhibitors are expected to exhibit efficacy against
inflammatory diseases due to their broad pharmacological activity. The launched PDE4 …

Background Pruritus is a recurring, long-lasting skin disease with few effective treatments.
Many patients have unsatisfactory responses to currently available antipruritic treatments …

Itching is a common clinical symptom in diabetic patients. This research is to carry out
experiments on the pathological changes in the P2Y12 receptor in type 2 diabetes mellitus …