Anti-obesity properties of phytochemicals: Highlighting their molecular mechanisms against obesity

E Poulios, S Koukounari, E Psara… - Current Medicinal …, 2024 - benthamdirect.com
Obesity is a complex, chronic and inflammatory disease that affects more than one-third of
the world's population, leading to a higher incidence of diabetes, dyslipidemia, metabolic …

Dietary conjugated linoleic acid and medium-chain triglycerides for obesity management

KS Ibrahim, EM El-Sayed - Journal of Biosciences, 2021 - Springer
Obesity is considered a serious global health issue. Patients have been predisposed to
comorbidities such as dyslipidemia, cardiovascular diseases, diabetes, cancers, and …

Effect of linoleic acid on cholesterol levels in a high-fat diet-induced hypercholesterolemia rat model

NA Azemi, AK Azemi, L Abu-Bakar, V Sevakumaran… - Metabolites, 2022 - mdpi.com
Cardiovascular disease is the leading cause of morbidity and mortality worldwide,
accounting for almost one-third of all deaths. The risk factors for developing this disease …

Whole grain qingke attenuates high-fat diet-induced obesity in mice with alterations in gut microbiota and metabolite profile

X Li, J Suo, X Huang, H Dai, H Bian, M Zhu… - Frontiers in …, 2021 - frontiersin.org
Whole grain Qingke (WGQK) displays anti-obesity and lipid-lowering properties; however,
the underlying mechanism remains elusive. This study investigated the alteration of gut …

Biorefining of essential polyunsaturated fatty acids from microbial sources: Current updates and prospects

AS Chauhan, AK Patel, V Nimker… - Systems Microbiology …, 2024 - Springer
The biorefinery approach ensures a sustainable source of valuable fatty acids and opens up
new avenues for their application in healthcare industries. Recent studies highlight the …

Profound perturbation in the metabolome of a canine obesity and metabolic disorder model

W Qu, Z Chen, X Hu, T Zou, Y Huang… - Frontiers in …, 2022 - frontiersin.org
Canine models are increasingly being used in metabolic studies due to their physiological
similarity with humans. The present study aimed to identify changes in metabolic pathways …

The effects of conjugated linoleic acid supplementation on anthropometrics and body composition indices in adults: a systematic review and dose–response meta …

O Asbaghi, G Shimi, FH Oskouie, K Naseri… - British Journal of …, 2024 - cambridge.org
Prior meta-analytic investigations over a decade ago rather inconclusively indicated that
conjugated linoleic acid (CLA) supplementation could improve anthropometric and body …

Metabolome and transcriptome signatures shed light on the anti-obesity effect of Polygonatum sibiricum

X Ou, X Wang, B Zhao, Y Zhao, H Liu… - Frontiers in Plant …, 2023 - frontiersin.org
Obesity has become one of the major threats to human health across the globe. The
rhizomes of Polygonatum sibiricum have shown promising anti-obesity effect. However, the …

Co‐option of PPARα in the regulation of lipogenesis and fatty acid oxidation in CLA‐induced hepatic steatosis

D Cai, Y Li, K Zhang, B Zhou, F Guo… - Journal of Cellular …, 2021 - Wiley Online Library
Abstract Nonalcoholic‐fatty‐liver‐disease (NAFLD) is the result of imbalances in hepatic
lipid partitioning and is linked to dietary factors. We demonstrate that conjugated linoleic …

Chaihu Shugan prevents cholesterol gallstone formation by ameliorating the microbiota dysbiosis and metabolic disturbance in mice

W Wang, K Zhang, B Liu, T Zhou, Y Tang… - Frontiers in …, 2024 - frontiersin.org
Introduction: Cholesterol gallstone (CGS) is a biliary tract disorder requiring treatment in
approximately 20% of patients. The efficacy of Chaihu Shugan in preventing CGS …