Multiple and complex aetiological processes underlie diabetes mellitus, which invariably
result in the development of hyperglycaemia. Although there are two prevalent distinct forms …

Alzheimer's disease (AD) has traditionally been considered solely a neurological condition.
Therefore, numerous studies have been conducted to identify the existence of …

Chronic kidney disease is a risk factor for cognitive impairment. Albuminuria is an early
manifestation of chronic kidney disease and a marker of endothelial dysfunction and …

Methylglyoxal (MG) is a reactive dicarbonyl metabolite formed during glucose, protein and
fatty acid metabolism. In hyperglycaemic conditions, increased MG level has been linked to …

Soluble cell adhesion molecules (sCAMs) are secreted ectodomain fragments of surface
adhesion molecules, ICAM1 and VCAM1. sCAMs have diverse immune functions beyond …

Abstract Background The Treatment Options for type 2 Diabetes in Adolescent and Youth
study, a randomized clinical trial of three treatments for type 2 diabetes (T2DM) in youth …

Background Nephropathy is a major complication of type 2 diabetes mellitus (T2DM) and is
heralded by the insidious development of microalbuminuria (MA). It is suggested that the …

Pituitary adenylate cyclase activating polypeptide (PACAP) is a neuropeptide, exerting
diverse effects. One of its frequently examined functions is cell protection, which is achieved …

Objective Endothelial dysfunction (ED) plays an important role in the pathogenesis of
diabetic nephropathy. The purpose of the study was to determine flow mediated endothelial …

Objective: Uncontrolled diabetes has become a major cause of mortality and morbidity by
reason of vascular angiopathy. The aim of this study was to evaluate the concentrations of …