The crystal–liquid–glass phase transition of coordination polymers (CPs) and metal–organic
frameworks (MOFs) offers attractive opportunities as a new class of amorphous materials …

Mechanochemistry is a promising alternative to solution-based protocols across the
chemical sciences, enabling different types of chemistries in solvent-free and …

Amorphous ices govern a range of cosmological processes and are potentially key materials
for explaining the anomalies of liquid water. A substantial density gap between low-density …

Drugs with low water solubility are predisposed to low and variable oral bioavailability and,
therefore, to variability in clinical response. Despite significant efforts to “design in” …

Co-amorphous drug delivery systems have recently gained considerable interest in the
pharmaceutical field because of their potential to improve oral bioavailability of poorly water …

It is now just about 10 years since the publication of the first edition of Polymorphism in
Pharmaceutical Solids, which certainly received a positive reaction from workers in drug …

The amorphous solid state offers an improved apparent solubility and dissolution rate.
However, due to thermodynamic instability and recrystallization tendencies during …

" Polymorphism in the Pharmaceutical Industry-Solid Form and Drug Development"
highlights the relevance of polymorphism in modern pharmaceutical chemistry, with a focus …

The number of active pharmaceutical substances having high therapeutic potential but low
water solubility is constantly increasing, making it difficult to formulate these compounds as …

A brief and systematic overview of recent advances in understanding the mechanism of
mechanochemical cocrystallization at macroscopic (bulk phase transformations) and …