Vaccination is one of the most efficient strategies for the prevention of infectious diseases.
Although safer, subunit vaccines are poorly immunogenic and for this reason the use of …

Adjuvants have been used for more than 70 yr to enhance the immune response of the host
animal to an antigen. Among the mechanisms that adjuvants use to enhance the immune …

The production of antibodies (Abs) in chickens and the extraction of specific Abs from egg
yolk (IgY Abs) are increasingly attracting the interest of the scientific community, as …

Antibodies are valuable tools in the laboratory and clinic. Antibodies include those secreted
by a single clone of B lymphocytes, termed monoclonal antibodies, and those produced by a …

Building upon the success of the Handbook of Laboratory Animal Science and completing
Volumes I and II of the Second Edition, Handbook of Laboratory Animal Science, Second …

Ever since its establishment by USDA regulation in the mid-1980s, the Institutional Animal
Care and Use Committee (IACUC) has evolved as the premier instrument of animal welfare …

In contrast to animal testing required by law to guarantee minimum safety standards for the
licensing of drugs and chemicals, there are no regulations in basic research forcing …

Chicken eggs present an ideal alternative antibody source to mammals, as the IgY in the
chicken's blood is transported to the egg and accumulates in the egg yolk in large quantities …

The multibillion-dollar global antibody industry produces an indispensable resource but that
is generated using millions of animals. Despite the irrefutable maturation and availability of …

El presente artículo reflexiona sobre las implicaciones éticas de usar modelos animales
para el desarrollo de la medicina en seres humanos. Entre las posturas extremas de …