Sympathetic Nervous System and Atherosclerosis

Y Wang, J Anesi, MC Maier, MA Myers… - International journal of …, 2023 - mdpi.com
Atherosclerosis is characterized by the narrowing of the arterial lumen due to subendothelial
lipid accumulation, with hypercholesterolemia being a major risk factor. Despite the recent …

Animal models, pathogenesis, and potential treatment of thoracic aortic aneurysm

Y Wang, IS Panicker, J Anesi, O Sargisson… - International Journal of …, 2024 - mdpi.com
Thoracic aortic aneurysm (TAA) has a prevalence of 0.16–0.34% and an incidence of 7.6
per 100,000 person-years, accounting for 1–2% of all deaths in Western countries …

Effect of Hydralazine on Angiotensin II-Induced Abdominal Aortic Aneurysm in Apolipoprotein E-Deficient Mice

Y Wang, O Sargisson, DT Nguyen, K Parker… - International Journal of …, 2023 - mdpi.com
The rupture of an abdominal aortic aneurysm (AAA) causes about 200,000 deaths
worldwide each year. However, there are currently no effective drug therapies to prevent …

The impact of inflammatory and oxidative stress biomarkers on the sympathetic nervous system in severe coronary atherosclerosis

AM Boieriu, C Dumitrel Luca, CD Neculoiu… - Frontiers in …, 2024 - frontiersin.org
Objective The present study aimed at evaluating the association between sympathetic
nervous system activation (SNS) and the severity of coronary artery disease (CAD). In …

[PDF][PDF] Special Issue “Sympathetic Nerves and Cardiovascular Diseases”

Y Wang, KM Denton - International Journal of Molecular Sciences, 2024 - mdpi.com
Cardiovascular diseases (CVDs) constitute a spectrum of disorders affecting the heart and
blood vessels, which include coronary heart disease, cerebrovascular disease, and …

Spatial metabolomics to discover hypertrophic scar relevant metabolic alterations and potential therapeutic strategies: A preliminary study

J Li, S Zeng, E Zhang, L Chen, J Jiang, J Li - Bioorganic Chemistry, 2024 - Elsevier
Spatially mapping the metabolic remodeling of hypertrophic scar and surrounding normal
skin tissues has the potential to enhance our comprehension of scar formation and aid in the …

Thermal Stability and Kinetics of Degradation of Moxonidine as Pure Ingredient vs. Pharmaceutical Formulation

B Baul, A Ledeţi, D Cîrcioban, A Ridichie, T Vlase… - Processes, 2023 - mdpi.com
The stability of active pharmaceutical ingredients (APIs) and the corresponding
pharmaceutical formulations are nowadays of great importance in pharmaceutical research …

Decoding vascular aging: implications for atherosclerosis progression and clinical intervention

SC Wankumbu, XM Ji, M Xu - Exploration of Drug Science, 2024 - explorationpub.com
Age-related pathologies, particularly cardiovascular disorders, pose a significant global
health concern. The World Health Organization (WHO) predicts an increase in advanced …

[PDF][PDF] Animal Models and Pathogenesis of Thoracic Aortic Aneurysm

Y Wang, IS Panicker, J Anesi, O Sargisson… - 2023 - preprints.org
Thoracic aortic aneurysm (TAA) has a prevalence of 0.16%-0.34% and an incidence of 7.6
per 100,000 person-years, accounting for 1%-2% of all deaths in Western countries …