Sensory neurons are activated by physical and chemical stimuli, eliciting sensations such as
temperature, touch, pain, and itch. From an evolutionary perspective, sensing danger is …

SARS-CoV-2 is a novel coronavirus that infects cells through the angiotensin-converting
enzyme 2 receptor, aided by proteases that prime the spike protein of the virus to enhance …

Primary somatosensory neurons are specialized to transmit specific types of sensory
information through differences in cell size, myelination, and the expression of distinct …

Neuropathic pain is a leading cause of high-impact pain, is often disabling and is poorly
managed by current therapeutics. Here we focused on a unique group of neuropathic pain …

Chemotherapy-induced peripheral neuropathy (CIPN) is an adverse side effect of many anti-
cancer chemotherapeutic treatments. CIPN often causes neuropathic pain in extremities …

Neuropathic pain (NeuP) arises due to injury of the somatosensory nervous system and is
both common and disabling, rendering an urgent need for non-addictive, effective new …

Dorsal root ganglion (DRG) neurons detect sensory inputs and are crucial for pain
processing. They are often studied in vitro as dissociated cell cultures with the assumption …

One of the first signs of viral infection is body-wide aches and pain. Although this type of pain
usually subsides, at the extreme, viral infections can induce painful neuropathies that can …

Nociceptors located in the trigeminal ganglion (TG) and DRG are the primary sensors of
damaging or potentially damaging stimuli for the head and body, respectively, and are key …

The peripheral somatosensory system bestows mammals with a diverse repertoire of
sensory modalities: gentle touch, mechanical pain, itch, thermosensation, and …