A variety of evolutionary processes has led to the development of different organs to ensure
that internal fertilization occur successfully. Fallopian tubes are a particularly interesting …

Fertilization in mammals requires the successful completion of many steps, starting with the
transport of gametes in the reproductive tract and ending with sperm-egg membrane fusion …

Mammalian oocytes are surrounded by an extracellular coat called the zona pellucida (ZP),
which, from an evolutionary point of view, is the most ancient of the coats that envelope …

The ubiquitin-proteasome pathway has been implicated in the penetration of ascidian
vitelline envelope by the fertilizing spermatozoon (Sawada et al., Proc Natl Acad Sci USA …

The process of fertilization begins when sperm contact the outermost egg investment and
ends with fusion of the two haploid pronuclei in the egg cytoplasm. Many steps in fertilization …

Sperm binding activity has been detected in zona pellucida (ZP) glycoproteins and it is
generally accepted that this activity resides in the carbohydrate moieties. In the present …

The zona pellucida (ZP) is an extracellular glycoprotein matrix that surrounds all mammalian
oocytes. Recent data have shown the presence of four glycoproteins (ZP1, ZP2, ZP3, and …

Fertilization in mammals requires sperm to bind to the zona pellucida (ZP) that surrounds the
egg. Galactose (Gal) or N-acetylglucosamine (GlcNAc) residues on the glycans of ZP protein …

Recent findings have refined our thinking on sperm interactions with the cumulus–oocyte
complex (COC) and our understanding of how, at the molecular level, the sperm cell …

Gamete recognition has been studied extensively in the mouse. In this system, it is generally
believed that sperm bind to a class of O-linked oligosaccharides on the zona pellucida …