Individuals born extremely preterm (before 28 weeks of gestation) comprise only about 0.7%
of births in the United States and an even lower proportion in other high resource countries …

Perinatal brain damage has been implicated in the pathogenesis of neurodevelopmental
impairments and psychiatric illnesses. This article reviews evidence that infection outside of …

Objective: Perinatal inflammation is a major risk factor for neurological deficits in preterm
infants. Several experimental studies have shown that systemic inflammation can alter the …

BACKGROUND: Extremely low gestational age newborns (ELGANs) are at increased risk
for structural and functional brain abnormalities. AIM: To identify factors that contribute to …

The neurovascular unit (NVU) plays a critical role in health and disease. In the current
review, we discuss the critical role of a class of neural/glial antigen 2 (NG2)-expressing glial …

Schizophrenia is a pervasive neurodevelopmental disorder that appears to result from
genetic and environmental factors. Although the dopamine hypothesis is the driving theory …

Objectives To evaluate whether in children born extremely preterm, indicators of sustained
systemic inflammation in the first month of life are associated with cognitive impairment at …

Background Diabetic cardiomyopathy (DCM) is a disorder of the heart muscle in people with
diabetes, which is characterized by both systolic and diastolic dysfunction. The effective …

There are currently no adequate treatments for white-matter injury, which often follows
central nervous system maladies and their accompanying neurodegenerative processes …

White matter damage is a clinically important aspect of several central nervous system
diseases, including stroke. Cerebral white matter primarily consists of axonal bundles …