Saliva is a complex fluid produced by 3 pairs of major salivary glands and by hundreds of
minor salivary glands. It comprises a large variety of constituents and physicochemical …

With the advancement of next-generation sequencing and mass spectrometry, there is a
growing need for the ability to merge biological features in order to study a system as a …

Objectives To provide an update on our current understanding of how saliva and its various
constituents directly and indirectly affect oral bacteria and thereby play a role in the …

The success of shotgun proteomic analysis depends largely on how samples are prepared.
Current approaches (such as those that are gel-, solution-, or filter-based), although being …

Animals live in symbiosis with numerous microbe species. While some can protect hosts
from infection and benefit host health, components of the microbiota or changes to the …

Bacteria can form single-and multispecies biofilms exhibiting diverse features based upon
the microbial composition of their community and microenvironment. The study of bacterial …

Early detection is crucial for the treatment and prognosis of oral cancer, a potentially lethal
condition. Tumor markers are abnormal biological byproducts produced by malignant cells …

Introduction Biological fluids are routine samples for diagnostic testing and monitoring.
Blood samples are typically measured because of their moderate invasive collection and …

Diverse commensal populations are now regarded as key to physiological homeostasis and
protection against disease. Although bacteria are the most abundant component of …

Microbial community structure can be analyzed by quantifying cell numbers or by quantifying
biomass for individual populations. Methods for quantifying cell numbers are already …