Computational Characterization of Membrane Proteins as Anticancer Targets: Current Challenges and Opportunities
M Gorostiola González, PRJ Rakers, W Jespers… - International Journal of …, 2024 - mdpi.com
Cancer remains a leading cause of mortality worldwide and calls for novel therapeutic
targets. Membrane proteins are key players in various cancer types but present unique …
targets. Membrane proteins are key players in various cancer types but present unique …
MCNN_MC: Computational Prediction of Mitochondrial Carriers and Investigation of Bongkrekic Acid Toxicity Using Protein Language Models and Convolutional …
Mitochondrial carriers (MCs) are essential proteins that transport metabolites across
mitochondrial membranes and play a critical role in cellular metabolism. ADP/ATP …
mitochondrial membranes and play a critical role in cellular metabolism. ADP/ATP …
[HTML][HTML] Homozygous slc25a20 zebrafish mutant reveals insights into carnitine-acylcarnitine translocase deficiency pathogenesis
R Hishida, K Ishiguro, T Yamanaka, S Toyokuni… - Molecular Genetics and …, 2024 - Elsevier
The SLC25A20 gene encodes carnitine-acylcarnitine translocase (CACT), facilitating the
transport of long-chain acylcarnitine required for energy production via β-oxidation into the …
transport of long-chain acylcarnitine required for energy production via β-oxidation into the …
Loss-of-function SLC25A20 mutation causes carnitine-acylcarnitine translocase deficiency by reducing SLC25A20 protein stability
Z Gan, X Wei, Y Zheng, Q Zheng, S Fan, F Xiong - Gene, 2024 - Elsevier
Background/aim Autosomal-recessive carnitine-acylcarnitine translocase deficiency
(CACTD) is a rare disorder of long-chain fatty acid oxidation caused by variants in the …
(CACTD) is a rare disorder of long-chain fatty acid oxidation caused by variants in the …
[HTML][HTML] Carnitine-acylcarnitine translocase deficiency
G Arnold - medlink.com
Carnitine-acylcarnitine translocase deficiency is a rare inborn error of energy metabolism
involving the carnitine cycle and long-chain fatty acid oxidation. This enzyme deficiency is …
involving the carnitine cycle and long-chain fatty acid oxidation. This enzyme deficiency is …