Abstract Immune cells contribute approximately 5–10% of the heart's total cell population,
including several myeloid cell and lymphocyte cell subsets, which, despite their relatively …

Accumulating evidence indicates that exosomes help to regulate bone homeostasis. The
roles of bone-derived exosomes have been well-described; however, recent studies have …

Osteonecrosis of the femoral head (ONFH) is a common complication of glucocorticoid (GC)
therapy. Recent advances demonstrate that sympathetic nerves regulate bone homeostasis …

Traumatic brain injury (TBI) leads to skeletal changes, including bone loss in the unfractured
skeleton, and paradoxically accelerates healing of bone fractures; however, the …

Aged patients often suffer poorer neurological recovery than younger patients after traumatic
brain injury (TBI), but the mechanisms underlying this difference remain unclear. Here, we …

In this review, we will summarize current and past findings on the adrenergic regulation of
myeloid cell functions and dynamics, with special emphasis on the pathophysiological …

A growing body of evidence suggests that patients who experience traumatic brain injuries
(TBIs) exhibit significantly shorter healing periods compared to those with isolated fractures …

Heterotopic ossification (HO) is a debilitating pathology where ectopic bone develops in
areas of soft tissue. HO can develop as a consequence of traumatic insult or as a result of …

Recent studies have highlighted the immunomodulatory effects of acupuncture on sepsis
and proposed novel non-pharmacological or bioelectronic approaches to managing …

Appropriate mechanical loading (ML) accelerates fracture healing. Macrophages, being the
primary mechanosensitive immune cells, play a pivotal role in the regulation of bone …