The catalytic functionalization of unreactive C− H bonds has recently brought a revolution in
synthetic methodologies for the production of pharmaceuticals and natural products and for …

The site-selective formation of carbonrcarbon bonds through direct functionalizations of
otherwise unreactive carbonrhydrogen bonds constitutes an economically attractive strategy …

The metal-catalysed successive activation and functionalisation of sp2 C–H bonds is the at
heart of synthetic innovations for the development of C–C bond cross-coupling processes …

Arylation of ortho C–H bonds is achieved by a ruthenium-catalyzed reaction of aromatic
amides having an 8-aminoquinoline moiety with aryl bromides. The reaction shows high …

Ruthenium-Catalyzed C–H Bond Arylations of Arenes Bearing Removable Directing Groups
via Six-Membered Ruthenacycles Page 1 10.1021/ol3000876 r 2012 American Chemical …

The ruthenium (II) carboxylate complex [Ru (O2CMes) 2 (p-cymene)] enabled efficient direct
arylations of unactivated C–H bonds with easily available, inexpensive phenols …

The ruthenium (II)-phosphine catalyst RuCl2 (PPh3)(p-cymene) operating water selectively
leads to ortho monoarylation, with arylchlorides and heteroarylhalides, of functional arenes …

Aryl chlorides are readily available at lower cost than the corresponding bromides and
iodides, but are much more challenging as substrates in metal-catalyzed cross-couplings …

The selective catalytic activation/functionalization of sp 2 C–H bonds is expected to improve
synthesis methods by better step number and atom economy. This chapter describes the …

Carboxylate assistance was key to success for highly efficient ruthenium-catalyzed direct
ortho-arylations of tetrazolyl-substituted arenes with aryl halides and triflates in the absence …