miRNAs as biomarkers in disease: latest findings regarding their role in diagnosis and prognosis

CE Condrat, DC Thompson, MG Barbu, OL Bugnar… - Cells, 2020 - mdpi.com
MicroRNAs (miRNAs) represent a class of small, non-coding RNAs with the main roles of
regulating mRNA through its degradation and adjusting protein levels. In recent years …

MicroRNAs and epigenetics strategies to reverse breast cancer

MM Rahman, AC Brane, TO Tollefsbol - Cells, 2019 - mdpi.com
Breast cancer is a sporadic disease with genetic and epigenetic components. Genomic
instability in breast cancer leads to mutations, copy number variations, and genetic …

A signature of four circulating microRNAs as potential biomarkers for diagnosing early-stage breast cancer

MM Itani, FJ Nassar, AH Tfayli, RS Talhouk… - International journal of …, 2021 - mdpi.com
Breast cancer (BC) is the most predominant type of cancer among women. The aim of this
study is to find new biomarkers that can help in early detection of BC, especially for those …

New therapy strategies in the management of breast cancer

S Yardim-Akaydin, B Karahalil, SN Baytas - Drug discovery today, 2022 - Elsevier
Breast cancer (BC), the second leading cause of cancer-related deaths after lung cancer, is
the most common cancer type among women worldwide. BC comprises multiple subtypes …

CircZFR functions as a sponge of miR-578 to promote breast cancer progression by regulating HIF1A expression

Z Chen, F Wang, Y Xiong, N Wang, Y Gu, X Qiu - Cancer cell international, 2020 - Springer
Background Breast cancer (BC) is the most common malignancy among women. Emerging
studies have demonstrated that circular RNA (circRNA) zinc finger RNA binding protein …

miR‑143‑5p suppresses breast cancer progression by targeting the HIF‑1α‑related GLUT1 pathway

J Xu, X Li, P Zhang, J Luo, E Mou… - Oncology …, 2022 - spandidos-publications.com
Breast cancer (BC) is a commonly identified life‑threatening type of cancer and a major
cause of death among women worldwide. Several microRNAs (miRs), including miR‑143 …

Exosomal microRNA-92b Is a Diagnostic Biomarker in Breast Cancer and Targets Survival-Related MTSS1L to Promote Tumorigenesis

JY Kan, SL Shih, SF Yang, PY Chu, FM Chen… - International Journal of …, 2024 - mdpi.com
Exosomal microRNAs (miRNAs) are novel, non-invasive biomarkers for facilitating
communication and diagnosing cancer. However, only a few studies have investigated their …

Comparison of oncogenes, tumor suppressors, and MicroRNAs between schizophrenia and glioma: the balance of power

JS Brown Jr - Neuroscience & Biobehavioral Reviews, 2023 - Elsevier
The risk of cancer in schizophrenia has been controversial. Confounders of the issue are
cigarette smoking in schizophrenia, and antiproliferative effects of antipsychotic medications …

Effect of P2X purinergic receptors in tumor progression and as a potential target for anti-tumor therapy

W Zhang - Purinergic Signalling, 2021 - Springer
The development of tumors is a complex pathological process involving multiple factors,
multiple steps, and multiple genes. Their prevention and treatment have always been a …

MiR-128-3p suppresses tumor proliferation and metastasis via targeting CDC6 in hepatocellular carcinoma cells

Y Shi, F Yan, F Wang, L Pan - Tissue and Cell, 2021 - Elsevier
Background MicroRNAs (miRNAs) are known to be involved in the pathogenesis of various
cancers. The present study devotes efforts to discover the role of miR-128-3p in …