Acylcarnitines are fatty acid metabolites that play important roles in many cellular energy
metabolism pathways. They have historically been used as important diagnostic markers for …

BACKGROUND Due to the rapidly increasing availability of metabolomics data in
prospective studies, an update of the meta evidence on metabolomics and type 2 diabetes …

Urolithin A (UA) is a natural compound produced by gut bacteria from ingested ellagitannins
(ETs) and ellagic acid (EA), complex polyphenols abundant in foods such as pomegranate …

Metabolic syndrome (MetS) is a cluster of cardiometabolic risk factors with high prevalence
among adult populations and elevated costs for public health systems worldwide. Despite …

The 1921 discovery of insulin was a Big Bang from which a vast and expanding universe of
research into insulin action and resistance has issued. In the intervening century, some …

Cardiomyocytes exit the cell cycle and become terminally differentiated soon after birth.
Therefore, in the adult heart, instead of an increase in cardiomyocyte number, individual …

Biomarker discovery and implementation are at the forefront of the precision medicine
movement. Modern advances in the field of metabolomics afford the opportunity to readily …

Urolithin A (UA) is a natural dietary, microflora-derived metabolite shown to stimulate
mitophagy and improve muscle health in old animals and in preclinical models of aging …

The discovery of insulin 100 years ago and its application to the treatment of human disease
in the years since have marked a major turning point in the history of medicine. The …

Increased dietary fiber consumption has been associated with many beneficial effects,
including amelioration of obesity and insulin resistance. These effects may be due to the …