Reuse of public genome-wide gene expression data

J Rung, A Brazma - Nature Reviews Genetics, 2013 - nature.com
Our understanding of gene expression has changed dramatically over the past decade,
largely catalysed by technological developments. High-throughput experiments …

Computational analysis of microarray data

J Quackenbush - Nature reviews genetics, 2001 - nature.com
Microarray experiments are providing unprecedented quantities of genome-wide data on
gene-expression patterns. Although this technique has been enthusiastically developed and …

An “Electronic Fluorescent Pictograph” browser for exploring and analyzing large-scale biological data sets

D Winter, B Vinegar, H Nahal, R Ammar, GV Wilson… - PloS one, 2007 - journals.plos.org
Background The exploration of microarray data and data from other high-throughput projects
for hypothesis generation has become a vital aspect of post-genomic research. For the non …

METLIN: a metabolite mass spectral database

CA Smith, G O'Maille, EJ Want, C Qin… - Therapeutic drug …, 2005 - journals.lww.com
Endogenous metabolites have gained increasing interest over the past 5 years largely for
their implications in diagnostic and pharmaceutical biomarker discovery. METLIN …

Minimum information about a microarray experiment (MIAME)—toward standards for microarray data

A Brazma, P Hingamp, J Quackenbush, G Sherlock… - Nature …, 2001 - nature.com
Microarray analysis has become a widely used tool for the generation of gene expression
data on a genomic scale. Although many significant results have been derived from …

Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma

TO Nielsen, FD Hsu, K Jensen, M Cheang… - Clinical cancer …, 2004 - AACR
Purpose: Expression profiling studies classified breast carcinomas into estrogen receptor
(ER)+/luminal, normal breast-like, HER2 overexpressing, and basal-like groups, with the …

Identification of genes periodically expressed in the human cell cycle and their expression in tumors

ML Whitfield, G Sherlock, AJ Saldanha… - Molecular biology of …, 2002 - Am Soc Cell Biol
The genome-wide program of gene expression during the cell division cycle in a human
cancer cell line (HeLa) was characterized using cDNA microarrays. Transcripts of> 850 …

Sharing detailed research data is associated with increased citation rate

HA Piwowar, RS Day, DB Fridsma - PloS one, 2007 - journals.plos.org
Background Sharing research data provides benefit to the general scientific community, but
the benefit is less obvious for the investigator who makes his or her data available. Principal …

Endothelial cell diversity revealed by global expression profiling

JT Chi, HY Chang, G Haraldsen… - Proceedings of the …, 2003 - National Acad Sciences
The vascular system is locally specialized to accommodate widely varying blood flow and
pressure and the distinct needs of individual tissues. The endothelial cells (ECs) that line the …

Gene expression patterns in human liver cancers

X Chen, ST Cheung, S So, ST Fan… - Molecular biology of …, 2002 - Am Soc Cell Biol
Hepatocellular carcinoma (HCC) is a leading cause of death worldwide. Using cDNA
microarrays to characterize patterns of gene expression in HCC, we found consistent …