Systemic insecticides (neonicotinoids and fipronil): trends, uses, mode of action and metabolites

N Simon-Delso, V Amaral-Rogers… - … Science and Pollution …, 2015 - Springer
Since their discovery in the late 1980s, neonicotinoid pesticides have become the most
widely used class of insecticides worldwide, with large-scale applications ranging from plant …

Neonicotinoids and other insect nicotinic receptor competitive modulators: progress and prospects

JE Casida - Annual Review of Entomology, 2018 - annualreviews.org
Neonicotinoids (neonics) are remarkably effective as plant systemics to control sucking
insects and for flea control on dogs and cats. The nitroimines imidacloprid, clothianidin …

Species sensitivity to toxic substances: Evolution, ecology and applications

D Spurgeon, E Lahive, A Robinson, S Short… - Frontiers in …, 2020 - frontiersin.org
Because it is only possible to test chemicals for effects on a restricted range of species and
exposure scenarios, ecotoxicologists are faced with a significant challenge of how to …

Neonicotinoids—from zero to hero in insecticide chemistry

P Jeschke, R Nauen - Pest Management Science: formerly …, 2008 - Wiley Online Library
In recent years, neonicotinoids have been the fastest‐growing class of insecticides in
modern crop protection, with widespread use against a broad spectrum of sucking and …

Recent developments in fluorine‐containing pesticides

P Jeschke - Pest Management Science, 2024 - Wiley Online Library
To ensure ongoing sustainability, the modern agrochemical industry is faced with enormous
challenges. These arise from provision of high‐quality food to increasing water use and …

Molecular recognition of neonicotinoid insecticides: the determinants of life or death

M Tomizawa, JE Casida - Accounts of chemical research, 2009 - ACS Publications
Until the mid-20th century, pest insect control in agriculture relied on largely inorganic and
botanical insecticides, which were inadequate. Then, the remarkable insecticidal properties …

Design, synthesis, characterization, and insecticidal bioefficacy screening of some new pyridine derivatives

AMK El-Dean, AA Abd-Ella, R Hassanien… - ACS …, 2019 - ACS Publications
A lot of insecticides are found nowadays, but neonicotinoids are considered the most
famous. So, a series of pyridine derivatives neonicotinoids analogues, namely, 3-cyano-4, 6 …

Synthesis and spectral characterization of selective pyridine compounds as bioactive agents

S Abdel-Raheem, A El-Dean… - Current Chemistry …, 2021 - m.growingscience.com
Starting from 3-cyano-4, 6-distyrylpyridin-2 (1H)-thione (1), the compound N-(4-
chlorophenyl)-2-((3-cyano-4, 6-distyrylpyridin-2-yl) thio) acetamide (2) was prepared …

Atomic interactions of neonicotinoid agonists with AChBP: molecular recognition of the distinctive electronegative pharmacophore

TT Talley, M Harel, RE Hibbs, Z Radić… - Proceedings of the …, 2008 - National Acad Sciences
Acetylcholine-binding proteins (AChBPs) from mollusks are suitable structural and functional
surrogates of the nicotinic acetylcholine receptors when combined with transmembrane …

Recent Progress in Diazirine‐Based Photoaffinity Labeling

M Hashimoto, Y Hatanaka - European journal of organic …, 2008 - Wiley Online Library
As a result of recent developments in molecular biology, the investigation of biofunctional
machinery at ligand‐accepting interfaces has become one of the challenging and important …