Objective To examine the cognitive profile of patients with myotonic dystrophy type 1 (DM1)
on the basis of a systematic review and meta-analysis of the literature. Methods Embase …

Objective: To systematically review brain imaging studies in myotonic dystrophy type 1
(DM1). Methods: We searched Embase (index period 1974–2016) and MEDLINE (index …

Myotonic dystrophies are multisystemic diseases characterized not only by muscle and heart
dysfunction but also by CNS alteration. They are now recognized as brain diseases affecting …

Neuroimaging in myotonic dystrophies provided a major contribution to the insight into brain
involvement which is highly prevalent in these multisystemic disorders. Particular in …

Myotonic dystrophy type-1 (DM1) is a genetic multi-systemic disorder involving several
organs including the brain. Despite the heterogeneity of this condition, some patients with …

Background Myotonic dystrophy type 1 (DM1) represents a multisystemic disorder in which
diffuse brain white and gray matter alterations related to clinical and genetic features have …

Myotonic dystrophy type 1 (DM1) is the most common muscular dystrophy that affects
multiple systems including the muscle and heart. The mutant CTG expansion at the 3′-UTR …

Brain function is compromised in myotonic dystrophy type 1 (DM1), but the underlying
mechanisms are not fully understood. To gain insight into the cellular and molecular …

Aim: To investigate the cortical thickness in myotonic dystrophy type 1 (DM1) and its
potential association with patients' genetic triplet expansion and social cognition deficits …

Objectives The aim of this study was to examine the natural history of brain involvement in
adult-onset myotonic dystrophies type 1 and 2 (DM1, DM2). Methods We conducted a …