Recent advances in polymer-based vaginal drug delivery systems

T Osmałek, A Froelich, B Jadach, A Tatarek… - Pharmaceutics, 2021 - mdpi.com
The vagina has been considered a potential drug administration route for centuries. Most of
the currently marketed and investigated vaginal formulations are composed with the use of …

[PDF][PDF] Drug delivery from the oral cavity: A focus on mucoadhesive

DM Shinkar, AS Dhake, CM Setty - PDA J. Pharm. Sci. Technol, 2012 - academia.edu
Since the early 1980s the concept of mucoadhesion has gained considerable interest in
pharmaceutical technology. The various advantages associated with these systems made …

[PDF][PDF] In vitro color changes of soft tissues caused by restorative materials

RE Jung, I Sailer, CHF Hammerle, T Attin… - … of Periodontics and …, 2007 - researchgate.net
A crucial factor influencing implant esthetics is the color of the peri-implant mucosa. This in
vitro study analyzed the effect of titanium and zirconia with and without veneering ceramic …

Distribution of Langerhans cells and mast cells within the human oral mucosa: new application sites of allergens in sublingual immunotherapy?

JP Allam, G Stojanovski, N Friedrichs, W Peng… - Allergy, 2008 - Wiley Online Library
Background: Sublingual immunotherapy (SLIT) represents an alternative to subcutaneous
immunotherapy. While antigen‐presenting cells such as Langerhans cells (LCs) are thought …

Recent options and techniques to assess improved bioavailability: In vitro and ex vivo methods

L Józsa, D Nemes, Á Pető, D Kósa, R Révész… - Pharmaceutics, 2023 - mdpi.com
Bioavailability assessment in the development phase of a drug product is vital to reveal the
disadvantageous properties of the substance and the possible technological interventions …

Sex differences in romantic kissing among college students: An evolutionary perspective

SM Hughes, MA Harrison… - Evolutionary …, 2007 - journals.sagepub.com
This study provides a descriptive account of kissing behavior in a large sample of
undergraduate college students and considers kissing in the context of both short-term and …

Quality by design of pranoprofen loaded nanostructured lipid carriers and their ex vivo evaluation in different mucosae and ocular tissues

M Rincón, LC Espinoza, M Silva-Abreu, L Sosa… - Pharmaceuticals, 2022 - mdpi.com
Transmucosal delivery is commonly used to prevent or treat local diseases. Pranoprofen is
an anti-inflammatory drug prescribed in postoperative cataract surgery, intraocular lens …

[PDF][PDF] Development and evaluation of buccoadhesive carvedilol tablets

V Yamsani, R Gannu, C Kolli, M Rao… - Acta Pharmaceutica, 2007 - sciendo.com
Buccoadhesive tablets of carvedilol were prepared using HPMC K4M, HPMC K15M and
Carbopol 934 as mucoadhesive polymers. Fifteen formulations were developed with varying …

Porcine vagina ex vivo as a model for studying permeability and pathogenesis in mucosa

CA Squier, MJ Mantz, PM Schlievert… - Journal of pharmaceutical …, 2008 - Elsevier
The vaginal mucosa is commonly exposed to a variety of topical agents, including chemical
contraceptives, drugs for the treatment of specific pathological conditions, and pathogenic …

Semifluorinated alkanes as new drug carriers—an overview of potential medical and clinical applications

C Tsagogiorgas, M Otto - Pharmaceutics, 2023 - mdpi.com
Fluorinated compounds have been used in clinical and biomedical applications for years.
The newer class of semifluorinated alkanes (SFAs) has very interesting physicochemical …