Huntington's disease is an autosomal dominant neurodegenerative disease caused by the
repetition of cytosine, adenine, and guanine trinucleotides on the short arm of chromosome …

This review explores the role of the antisaccadic task in understanding inhibitory
mechanisms in basal ganglia disorders. It conducts a comparative analysis of saccadic …

The growing number of people with cognitive impairment will significantly increase
healthcare demand. Screening tools are crucial for detecting cognitive impairment due to a …

Objective The clinical manifestation of amyotrophic lateral sclerosis (ALS) is characterized
by motor neuron degeneration, whereas frontotemporal dementia (FTD) patients show …

Objective To investigate cognitive flexibility in premanifest and manifest Huntington's
disease (HD). Background HD is an autosomal dominant neurodegenerative disease …

Ophthalmologic and neuro-ophthalmic evaluation is evolving as an important part of the
early diagnosis and management of people with dementia. A particular focus on ocular …

The unified model of time processing suggests that the striatum is a central structure
involved in all tasks that require the processing of temporal durations. Patients with …

The first group is generally reflexive or automatic and includes activation of older central
nervous system (CNS) structures, whereas saccades, especially voluntary saccades …

Background: Huntington's disease (HD) is characterized by a loss of control of motor
function that causes the presence of abnormal eye movements at early stages. Objective: To …

Objectives: Huntington's disease (HD) is an autosomal dominant neurodegenerative
disorder that affects first basal ganglia and fronto-striatal circuitry. Cognitive decline and …